All hotels In Southwest Illinois, Illinois
There are 646 hotels in Southwest Illinois
- Drury Inn & Suites Sikeston, MO
- Hampton Inn & Suites St. Louis/Alton
- SpringHill Suites by Marriott St. Louis Airport/Earth City
- Fairfield Inn & Suites St Louis Westport
- Harrah's Metropolis Hotel & Casino
- Holiday Inn Express Metropolis by IHG
- Comfort Inn Festus - St Louis South
- The Lodge at Grant's Trail
- Sonesta Simply Suites St Louis Earth City
- Courtyard by Marriott Cape Girardeau Downtown
- Drury Inn & Suites Jackson MO
- The Last Hotel
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Baymont by Wyndham Litchfield
- Super 8 by Wyndham Metropolis
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- Residence Inn by Marriott St Louis Airport
- Hampton Inn by Hilton Litchfield
- Cobblestone Inn & Suites - Altamont
- WoodSpring Suites St. Louis Arnold
- Hampton Inn St. Louis Southwest
- Comfort Inn Alton near I-255
- Motel 6 Metropolis, IL
- Comfort Inn & Suites Sikeston I-55
- Silo Farm Haus- located in the heart of wine country!
- Quality Inn Litchfield Route 66
- OYO Hotel St. Louis Downtown City Center MO
- Quality Inn Perryville I-55
- Quality Inn
- Indoor Heated Pool pontoon boat fish 3 full baths sleeps 17 in beds 2025 SALE!!!
- Super 8 by Wyndham Jerseyville
- Baymont by Wyndham Metropolis
- Carlin Villa Motel
- St. Louis Airport Hotel