Book Holiday Homes in Cape Girardeau

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Featured Holiday Homes in Cape Girardeau

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau
The price is AU$391 per night from 17 Apr to 18 Apr
AU$391
includes taxes & fees
17 Apr - 18 Apr
When you stay at this vacation home in Cape Girardeau, you'll be on a river, just steps from Shawnee National Forest and Mississippi River.
Serenity South -- Gardens, River-Views, and Refreshing Space
Notting Hill Cottage

Notting Hill Cottage

Alto Pass
With a stay at this vacation home in Alto Pass, you'll be a 1-minute drive from Shawnee National Forest and 6 minutes from Peachbarn Winery.
Notting Hill Cottage
Beautiful location in the secluded woods

Beautiful location in the secluded woods

Pomona
The price is AU$289 per night from 22 Apr to 23 Apr
AU$289
includes taxes & fees
22 Apr - 23 Apr
When you stay at this vacation home in Pomona, you'll be 1 minutes by foot from Shawnee National Forest.
Beautiful location in the secluded woods
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* On the Wine Trail * Hot Tub * Wi-Fi *

* On the Wine Trail * Hot Tub * Wi-Fi *

Alto Pass
With a stay at this vacation home, you'll be centrally located in Alto Pass, steps from Shawnee National Forest and 15 minutes by foot from Peachbarn ...
* On the Wine Trail * Hot Tub * Wi-Fi *
Wine Trail, Cozy Cabin plus hot tub

Wine Trail, Cozy Cabin plus hot tub

Cobden
With a stay at this vacation home in Cobden, you'll be within a 10-minute drive of Shawnee National Forest and Owl Creek Vineyard.
Wine Trail, Cozy Cabin plus hot tub
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *

* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *

Alto Pass
With a stay at this vacation home, you'll be centrally located in Alto Pass, steps from Shawnee National Forest and 15 minutes by foot from Peachbarn ...
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural

Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural

Cobden
Located in Cobden, this vacation home is in a rural location, a 1-minute drive from Shawnee National Forest and 9 minutes from StarView Vineyards.
Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Cape Girardeau
The price is AU$372 per night from 30 Apr to 1 May
AU$372
includes taxes & fees
30 Apr - 1 May
Located in Cape Girardeau, this vacation home is in a rural location, within a 5-minute drive of Twin Trees Park and Shawnee National Forest.
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Cape Girardeau
With a stay at this vacation home in Cape Girardeau, you'll be within a 5-minute drive of Shawnee National Forest and Mississippi River.
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cape Girardeau Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Cape Girardeau vacation homes are the perfect way for you to wing it.

Holiday houses in Cape Girardeau let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Cape Girardeau in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Cape Girardeau adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Cape Girardeau with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Cape Girardeau vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Cape Girardeau Holiday Homes essential information

Accommodation
53 Holiday Homes
Lowest Price
AU$104
Highest Price
AU$391
Popular accommodation
Serenity South -- Gardens, River-Views, and Refreshing Space, Notting Hill Cottage, Beautiful location in the secluded woods , * On the Wine Trail * Hot Tub * Wi-Fi *, Wine Trail, Cozy Cabin plus hot tub, * Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *, Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural, 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool, 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Top trending hotels in Cape Girardeau

The Riverview

The Riverview

3.5 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$171 per night from 4 May to 5 May
AU$171
includes taxes & fees
4 May - 5 May
When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Shawnee National Forest and Mississippi ...
The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$169 per night from 20 Apr to 21 Apr
AU$169
includes taxes & fees
20 Apr - 21 Apr
When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive ...
Drury Plaza Hotel Cape Girardeau Conference Center
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street, Cape Girardeau, MO
Fully refundable
The price is AU$183 per night from 11 May to 12 May
AU$183
includes taxes & fees
11 May - 12 May
When you stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Shawnee ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
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Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$104 per night from 27 Apr to 28 Apr
AU$104
includes taxes & fees
27 Apr - 28 Apr
With a stay at Pear Tree Inn Cape Girardeau Near the Medical Center, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National ...
Pear Tree Inn Cape Girardeau Near the Medical Center
Don't see what you're looking for?
See all available properties in Cape Girardeau
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.