Book Holiday Homes in De Soto

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Featured Holiday Homes in De Soto

Cute spacious Ranch - very safe area - 4 BR 2B- big fenced yard -1800 sft

Cute spacious Ranch - very safe area - 4 BR 2B- big fenced yard -1800 sft

High Ridge
The price is AU$477 per night from 23 Nov to 24 Nov
AU$477
includes taxes & fees
23 Nov - 24 Nov
Located in High Ridge, this vacation home is within a 5-minute drive of Jefferson County Library Northwest Branch and High Ridge Civic Center & Park.
Cute spacious Ranch - very safe area - 4 BR 2B- big fenced yard -1800 sft
Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill

Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill

2 out of 5
Byrnes Mill
The price is AU$409 per night from 2 Dec to 3 Dec
AU$409
includes taxes & fees
2 Dec - 3 Dec
Located in House Springs, this vacation home is within a 15-minute walk of Brynes Mill Park and Big River.
Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill
Come stay at The White House. Old World Charm in fabulous Farmington

Come stay at The White House. Old World Charm in fabulous Farmington

2 out of 5
Farmington
The price is AU$404 per night from 23 Nov to 24 Nov
AU$404
includes taxes & fees
23 Nov - 24 Nov
With a stay at this vacation home in Farmington, you'll be a 5-minute walk from Harlan Park and 6 minutes by foot from Farmington Skate Park.
Come stay at The White House. Old World Charm in fabulous Farmington
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Clifford's Country Cottage

Clifford's Country Cottage

2.5 out of 5
Bonne Terre
Located in Bonne Terre, this vacation home is in a rural location, a 4-minute drive from Big River and 10 minutes from Bonne Terre Mine.
Clifford's Country Cottage
Peter Ray House

Peter Ray House

Maeystown
With a stay at this vacation home, you'll be centrally located in Maeystown, 7.2 mi (11.5 km) from Mississippi River and 6.4 mi (10.2 km) from Illinois Caverns ...
Peter Ray House
Beautiful historical two story stone farmhouse

Beautiful historical two story stone farmhouse

Bonne Terre
The price is AU$611 per night from 24 Nov to 25 Nov
AU$611
includes taxes & fees
24 Nov - 25 Nov
Located in Bonne Terre, this vacation home is in a rural location, within a 5-minute drive of Big River and Bonne Terre Mine.
Beautiful historical two story stone farmhouse
Charming small town! Whole house

Charming small town! Whole house

Maeystown
The price is AU$256 per night from 1 Dec to 2 Dec
AU$256
includes taxes & fees
1 Dec - 2 Dec
When you stay at this vacation home in Maeystown, you'll be 14 minutes by car from Illinois Caverns State Natural Area.
Charming small town! Whole house
Tiny Houses of French Village

Tiny Houses of French Village

2.5 out of 5
5953 Brickey Rd, French Village, MO
The price is AU$469 per night from 24 Nov to 25 Nov
AU$469
includes taxes & fees
24 Nov - 25 Nov
With a stay at Tiny Houses of French Village in French Village, you'll be 15.3 mi (24.6 km) from Mississippi River and 11.4 mi (18.3 km) from Big River.
Tiny Houses of French Village
Cozy town house - 3 Queen beds

Cozy town house - 3 Queen beds

Barnhart
The price is AU$275 per night from 5 Dec to 6 Dec
AU$275
includes taxes & fees
5 Dec - 6 Dec
With a stay at this vacation home in Barnhart, you'll be within a 10-minute drive of Mississippi River and Jefferson County Library Windsor Branch.
Cozy town house - 3 Queen beds
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

De Soto Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our De Soto vacation homes are the perfect way for you to wing it.

Holiday houses in De Soto let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of De Soto in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local De Soto adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in De Soto with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of De Soto vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

De Soto Holiday Homes essential information

Accommodation
48 Holiday Homes
Lowest Price
AU$211
Highest Price
AU$611
Popular accommodation
Cute spacious Ranch - very safe area - 4 BR 2B- big fenced yard -1800 sft , Charming 3-bedroom house with WiFi, and fenced-in backyard in serene Byrnes Mill, Come stay at The White House. Old World Charm in fabulous Farmington, Clifford's Country Cottage, Peter Ray House, Beautiful historical two story stone farmhouse, Charming small town! Whole house , Tiny Houses of French Village, Cozy town house - 3 Queen beds

Top trending hotels in De Soto

Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel

Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel

3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
Fully refundable
The price is AU$211 per night from 19 Dec to 20 Dec
AU$211
includes taxes & fees
19 Dec - 20 Dec
Located in De Soto, Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel is on a lake, within a 15-minute drive of Valle Lake Beach and Eastside ...
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Secluded cabin on private property

Secluded cabin on private property

De Soto
When you stay at this cabin in De Soto, you'll be 3 minutes by foot from Big River.
Secluded cabin on private property
82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto
The price is AU$427 per night from 24 Nov to 25 Nov
AU$427
includes taxes & fees
24 Nov - 25 Nov
Located in De Soto, this cabin is in a rural location, within a 10-minute drive of Eastside Community Park and Joachim Park.
82 Acre Hobby Farm with Lincoln Log Cabin
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Traditional Country Home in De Soto w/ Yard!

Traditional Country Home in De Soto w/ Yard!

De Soto
With a stay at this vacation home in De Soto, you'll be within a 15-minute drive of Railroad Workers Memorial Park and Joachim Park.
Traditional Country Home in De Soto w/ Yard!
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See all available properties in De Soto
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.