Book Holiday Homes in O Brien

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Featured Holiday Homes in O Brien

Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock

Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock

Branford
When you a stay at this vacation home in Branford, you'll be on the waterfront, just steps from Santa Fe River and Fort White Wildlife and Environmental ...
Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock
Ginnie Springs Hidden Scuba Oasis Retreat!   Only 1 minute from Ginnie Springs

Ginnie Springs Hidden Scuba Oasis Retreat! Only 1 minute from Ginnie Springs

High Springs
With a stay at this vacation home in High Springs, you'll be on a lake, within a 10-minute drive of Ginnie Spring and Ruth B. Kirby Gilchrist Blue Springs State ...
Ginnie Springs Hidden Scuba Oasis Retreat! Only 1 minute from Ginnie Springs
The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee

The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee

Branford
Located in Branford, this vacation home is on the waterfront, within a 15-minute drive of Ichetucknee River and William Guy Lemmon Memorial Park.
The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee
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Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️

Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️

High Springs
The price is AU$401 per night from 15 Apr to 16 Apr
AU$401
includes taxes & fees
15 Apr - 16 Apr
When you a stay at this vacation home in High Springs, you'll be on a river, just steps from High Springs Library Branch and High Springs City Hall.
Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️
Bunkhouse Farm Stay

Bunkhouse Farm Stay

Fort White
Located in Fort White, this vacation home is on a river, within a 15-minute drive of O'Leno State Park and Columbia Rise.
Bunkhouse Farm Stay
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

Fort White,
When you a stay at this vacation home in Fort White, you'll be on a river, just steps from Ichetucknee Springs State Park and Ichetucknee River.
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River
Secluded and very unique OFF grid country home, 15 springs within an hour.

Secluded and very unique OFF grid country home, 15 springs within an hour.

MAYO
When you stay at this vacation home in Mayo, you'll be on the waterfront, within a 5-minute drive of Suwannee River and Lafayette Blue Springs State Park.
Secluded and very unique OFF grid country home, 15 springs within an hour.
Pet-Friendly Florida Escape w/ Patio & Fire Pit!

Pet-Friendly Florida Escape w/ Patio & Fire Pit!

O'Brien
Located in O Brien, this vacation home is a 4-minute drive from Ichetucknee Springs State Park and 7 minutes from Santa Fe River.
Pet-Friendly Florida Escape w/ Patio & Fire Pit!
Modern & Convenient 3/2 Home

Modern & Convenient 3/2 Home

Lake City
Located in Lake City, this vacation home is within a 5-minute drive of Lake City Columbia County Historical Museum and Columbia County Courthouse.
Modern & Convenient 3/2 Home
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

O Brien Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our O Brien vacation homes are the perfect way for you to wing it.

Holiday houses in O Brien let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of O Brien in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local O Brien adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in O Brien with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of O Brien vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

O Brien Holiday Homes essential information

Accommodation
141 Holiday Homes
Lowest Price
AU$191
Highest Price
AU$723
Popular accommodation
Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock, Ginnie Springs Hidden Scuba Oasis Retreat! Only 1 minute from Ginnie Springs, The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee, Walking distance to Brewery and Restaurants ⭐️⭐️⭐️⭐️⭐️, Bunkhouse Farm Stay, ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River, Secluded and very unique OFF grid country home, 15 springs within an hour., Pet-Friendly Florida Escape w/ Patio & Fire Pit!, Modern & Convenient 3/2 Home

Top trending hotels in O Brien

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

obrien
When you stay at this vacation home in O Brien, you'll be on the beach and steps from Suwannee River.
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
Pet-Friendly Florida Escape w/ Patio & Fire Pit!

Pet-Friendly Florida Escape w/ Patio & Fire Pit!

O'Brien
Located in O Brien, this vacation home is a 4-minute drive from Ichetucknee Springs State Park and 7 minutes from Santa Fe River.
Pet-Friendly Florida Escape w/ Patio & Fire Pit!
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

O'Brien
The price is AU$723 per night from 8 Apr to 9 Apr
AU$723
includes taxes & fees
8 Apr - 9 Apr
When you stay at this vacation home in O Brien, you'll be steps from Suwannee River.
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
Save an average of 15% on thousands of hotels when you're signed in
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE, Lake City, FL
Fully refundableReserve now, pay when you stay
The price is AU$191 per night from 20 Apr to 21 Apr
AU$191
includes taxes & fees
20 Apr - 21 Apr
With a stay at La Quinta Inn & Suite by Wyndham Lake City in Lake City, you'll be a 5-minute walk from Fresenius Medical Care at Lake City Medical Center and ...
La Quinta Inn & Suite by Wyndham Lake City
Don't see what you're looking for?
See all available properties in O Brien
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.