Book Holiday Homes in Panama City

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Panama City Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Panama City vacation homes are the perfect way for you to wing it.

Holiday houses in Panama City let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Panama City in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Panama City adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Panama City with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Panama City vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Panama City Holiday Homes essential information

Accommodation
Holiday Homes
Lowest Price
AU$134
Highest Price
AU$229
Popular accommodation
La Quinta Inn & Suites by Wyndham Panama City, Hilton Garden Inn Panama City Airport, Best Western Plus Panama City Hotel, Days Inn by Wyndham Panama City

Top trending hotels in Panama City

La Quinta Inn & Suites by Wyndham Panama City

La Quinta Inn & Suites by Wyndham Panama City

3 out of 5
1030 E 23rd St, Panama City, FL
Fully refundableReserve now, pay when you stay
The price is AU$188 per night from 6 Apr to 7 Apr
AU$188
includes taxes & fees
6 Apr - 7 Apr
A stay at La Quinta Inn & Suites by Wyndham Panama City places you in the heart of Panama City, within a 15-minute walk of Panama City Mall and Linos Park.
La Quinta Inn & Suites by Wyndham Panama City
Hilton Garden Inn Panama City Airport

Hilton Garden Inn Panama City Airport

3 out of 5
5625 Venture Crossings Blvd, Panama City, FL
Fully refundableReserve now, pay when you stay
The price is AU$229 per night from 5 May to 6 May
AU$229
includes taxes & fees
5 May - 6 May
Located in Panama City, Hilton Garden Inn Panama City Airport is within a 15-minute drive of St. Andrews Bay and Museum of Man in the Sea.
Hilton Garden Inn Panama City Airport
Best Western Plus Panama City Hotel

Best Western Plus Panama City Hotel

2.5 out of 5
Mercedes Avenue, 2338, Panama City, FL
Fully refundableReserve now, pay when you stay
The price is AU$151 per night from 6 Apr to 7 Apr
AU$151
includes taxes & fees
6 Apr - 7 Apr
When you stay at Best Western Plus Panama City Hotel in Panama City, you'll be near the airport, within a 5-minute drive of Panama City Mall and Linos Park.
Best Western Plus Panama City Hotel
Save an average of 15% on thousands of hotels when you're signed in
Days Inn by Wyndham Panama City

Days Inn by Wyndham Panama City

2.5 out of 5
1035 East 23rd St., Panama City, FL
Fully refundableReserve now, pay when you stay
The price is AU$134 per night from 6 Apr to 7 Apr
AU$134
includes taxes & fees
6 Apr - 7 Apr
With a stay at Days Inn by Wyndham Panama City in Panama City, you'll be within a 5-minute drive of Panama City Mall and Linos Park.
Days Inn by Wyndham Panama City
Don't see what you're looking for?
See all available properties in Panama City
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.