Book Holiday Homes in Picayune

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Featured Holiday Homes in Picayune

On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property

On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property

Pass Christian
With a stay at this vacation home in Pass Christian, you'll be on the beach, within a 15-minute drive of Gulfport Beach and Thou Art Gallery & GIfts.
On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property
On Main St! Private Heated pool, Golf cart included, Sleeps 10

On Main St! Private Heated pool, Golf cart included, Sleeps 10

Bay St. Louis
A stay at this vacation home places you in the heart of Bay St Louis, within a 10-minute walk of Alice Moseley Folk Art and Antique Museum and 100 Men D.B.A. ...
On Main St! Private Heated pool, Golf cart included, Sleeps 10
Cheerful 4 Bedroom Home in Downtown Depot District

Cheerful 4 Bedroom Home in Downtown Depot District

Bay St. Louis
A stay at this vacation home places you in the heart of Bay St Louis, steps from Bay St. Louis Little Theater and 6 minutes by foot from Alice Moseley Folk Art ...
Cheerful 4 Bedroom Home in Downtown Depot District
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St George Cottage

St George Cottage

Bay St. Louis
With a stay at this vacation home in Bay St Louis, you'll be within a 15-minute walk of Alice Moseley Folk Art and Antique Museum and 100 Men D.B.A. Hall.
St George Cottage
Kick off the new year in BSL at this beautiful dog-friendly cottage

Kick off the new year in BSL at this beautiful dog-friendly cottage

Bay St. Louis
A stay at this vacation home places you in the heart of Bay St Louis, within a 15-minute walk of Bay St. Louis Little Theater and Alice Moseley Folk Art and ...
Kick off the new year in BSL at this beautiful dog-friendly cottage
Beachfront 1 bedroom on the beach in Bay St Louis. Walking distance to Main St!

Beachfront 1 bedroom on the beach in Bay St Louis. Walking distance to Main St!

Bay St Louis
With a stay at this vacation home in Bay St Louis (Old Town Bay St Louis), you'll be a 5-minute walk from Saint Stanislaus College and 10 minutes by foot from ...
Beachfront 1 bedroom on the beach in Bay St Louis. Walking distance to Main St!
New Beachfront 3 Bed 2 1/2 Bath in downtown Bay St Louis in Prime Location

New Beachfront 3 Bed 2 1/2 Bath in downtown Bay St Louis in Prime Location

Bay St Louis
With a stay at this vacation home in Bay St Louis (Old Town Bay St Louis), you'll be a 5-minute walk from Saint Stanislaus College and 10 minutes by foot from ...
New Beachfront 3 Bed 2 1/2 Bath in downtown Bay St Louis in Prime Location
Peggy  Sue

Peggy Sue

Pass Christian
The price is AU$372 per night from 24 Feb to 25 Feb
AU$372
includes taxes & fees
24 Feb - 25 Feb
With a stay at this vacation home in Pass Christian, you'll be within a 15-minute drive of Gulfport Beach and Thou Art Gallery & GIfts.
Peggy Sue
Location! Wonderful, Comfortable, Spacious House!

Location! Wonderful, Comfortable, Spacious House!

Bay Saint Louis
A stay at this vacation home places you in the heart of Bay St Louis, within a 10-minute walk of Bay Saint Louis Municipal Harbor and Alice Moseley Folk Art ...
Location! Wonderful, Comfortable, Spacious House!
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Picayune Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Picayune vacation homes are the perfect way for you to wing it.

Holiday houses in Picayune let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Picayune in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Picayune adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Picayune with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Picayune vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Picayune Holiday Homes essential information

Accommodation
476 Holiday Homes
Lowest Price
AU$77
Highest Price
AU$372
Popular accommodation
On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property, On Main St! Private Heated pool, Golf cart included, Sleeps 10, Cheerful 4 Bedroom Home in Downtown Depot District, St George Cottage, Kick off the new year in BSL at this beautiful dog-friendly cottage, Beachfront 1 bedroom on the beach in Bay St Louis. Walking distance to Main St!, New Beachfront 3 Bed 2 1/2 Bath in downtown Bay St Louis in Prime Location, Peggy Sue, Location! Wonderful, Comfortable, Spacious House!

Top trending hotels in Picayune

Holiday Inn Express Picayune-Stennis Space Center, an IHG Hotel

Holiday Inn Express Picayune-Stennis Space Center, an IHG Hotel

2.5 out of 5
1001 Dauphin Street, Picayune, MS
Fully refundable
The price is AU$163 per night from 9 Mar to 10 Mar
AU$163
includes taxes & fees
9 Mar - 10 Mar
With a stay at Holiday Inn Express Picayune-Stennis Space Center by IHG in Picayune, you'll be within a 5-minute drive of Teddy Bear Museum and Shay Park.
Holiday Inn Express Picayune-Stennis Space Center, an IHG Hotel
Days Inn by Wyndham Picayune

Days Inn by Wyndham Picayune

2 out of 5
450 S Lofton Avenue, Picayune, MS
Fully refundableReserve now, pay when you stay
The price is AU$85 per night from 24 Feb to 25 Feb
AU$85
includes taxes & fees
24 Feb - 25 Feb
Located in Picayune, Days Inn by Wyndham Picayune is within a 5-minute drive of Leola Jordan Park and Teddy Bear Museum.
Days Inn by Wyndham Picayune
Heritage Inn Picayune

Heritage Inn Picayune

2 out of 5
1122 Memorial Blvd., Picayune, MS
Fully refundableReserve now, pay when you stay
The price is AU$141 per night from 25 Mar to 26 Mar
AU$141
includes taxes & fees
25 Mar - 26 Mar
With a stay at Heritage Inn Picayune in Picayune, you'll be within a 5-minute drive of Teddy Bear Museum and Leola Jordan Park.
Heritage Inn Picayune
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Super 8 by Wyndham Picayune

Super 8 by Wyndham Picayune

2 out of 5
999 Cooper Road, Picayune, MS
Fully refundableReserve now, pay when you stay
The price is AU$77 per night from 12 Mar to 13 Mar
AU$77
includes taxes & fees
12 Mar - 13 Mar
A stay at Super 8 by Wyndham Picayune places you in the heart of Picayune, a 4-minute drive from Millbrook Country Club and 7 minutes from Crosby Arboretum.
Super 8 by Wyndham Picayune
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.