Book Holiday Homes in Picayune

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Featured Holiday Homes in Picayune

On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property

On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property

Pass Christian
When you stay at this vacation home in Pass Christian, you'll be on the beach, within a 5-minute drive of Thou Art Gallery & GIfts and War Memorial Park.
On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property
On Main St! Private Heated pool, Golf cart included, Sleeps 10

On Main St! Private Heated pool, Golf cart included, Sleeps 10

Bay St. Louis
A stay at this vacation home places you in the heart of Bay St Louis, within a 10-minute walk of Alice Moseley Folk Art and Antique Museum and 100 Men D.B.A. ...
On Main St! Private Heated pool, Golf cart included, Sleeps 10
Cheerful 4 Bedroom Home in Downtown Depot District

Cheerful 4 Bedroom Home in Downtown Depot District

Bay St. Louis
A stay at this vacation home places you in the heart of Bay St Louis, steps from Bay St. Louis Little Theater and 6 minutes by foot from Alice Moseley Folk Art ...
Cheerful 4 Bedroom Home in Downtown Depot District
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St George Cottage

St George Cottage

Bay St. Louis
With a stay at this vacation home in Bay St Louis, you'll be within a 15-minute walk of Alice Moseley Folk Art and Antique Museum and 100 Men D.B.A. Hall.
St George Cottage
New Beachfront 3 Bed 2 1/2 Bath in downtown Bay St Louis in Prime Location

New Beachfront 3 Bed 2 1/2 Bath in downtown Bay St Louis in Prime Location

Bay St Louis
With a stay at this vacation home in Bay St Louis (Old Town Bay St Louis), you'll be a 5-minute walk from Saint Stanislaus College and 10 minutes by foot from ...
New Beachfront 3 Bed 2 1/2 Bath in downtown Bay St Louis in Prime Location
Peggy  Sue

Peggy Sue

Pass Christian
The price is AU$382 per night from 20 Jan to 21 Jan
AU$382
includes taxes & fees
20 Jan - 21 Jan
With a stay at this vacation home in Pass Christian, you'll be within a 5-minute drive of Thou Art Gallery & GIfts and War Memorial Park.
Peggy Sue
Location! Wonderful, Comfortable, Spacious House!

Location! Wonderful, Comfortable, Spacious House!

Bay Saint Louis
A stay at this vacation home places you in the heart of Bay St Louis, within a 10-minute walk of Bay Saint Louis Municipal Harbor and Alice Moseley Folk Art ...
Location! Wonderful, Comfortable, Spacious House!
HEATED POOL, Hot Tub, BOAT/FISH DOCK, Gourmet Kitchen, Pet and Family Friendly

HEATED POOL, Hot Tub, BOAT/FISH DOCK, Gourmet Kitchen, Pet and Family Friendly

Pass Christian
Located in Pass Christian, this vacation home is by the sea, within a 10-minute drive of Portage Marina and Thou Art Gallery & GIfts.
HEATED POOL, Hot Tub, BOAT/FISH DOCK, Gourmet Kitchen, Pet and Family Friendly
Charming Coastal Camp~Pet Friendly, Deep Water Access: Jourdan/Gulf-Private Dock

Charming Coastal Camp~Pet Friendly, Deep Water Access: Jourdan/Gulf-Private Dock

Bay St. Louis
Located in Bay St Louis, this vacation home is on the waterfront, within a 15-minute drive of Ochsner Medical Center - Hancock and Bay St. Louis Little ...
Charming Coastal Camp~Pet Friendly, Deep Water Access: Jourdan/Gulf-Private Dock
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Picayune Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Picayune vacation homes are the perfect way for you to wing it.

Holiday houses in Picayune let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Picayune in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Picayune adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Picayune with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Picayune vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Picayune Holiday Homes essential information

Accommodation
470 Holiday Homes
Lowest Price
AU$76
Highest Price
AU$382
Popular accommodation
On the Beach, Teddy Roosevelt Stayed Here. Pet friendly, large fenced property, On Main St! Private Heated pool, Golf cart included, Sleeps 10, Cheerful 4 Bedroom Home in Downtown Depot District, St George Cottage, New Beachfront 3 Bed 2 1/2 Bath in downtown Bay St Louis in Prime Location, Peggy Sue, Location! Wonderful, Comfortable, Spacious House! , HEATED POOL, Hot Tub, BOAT/FISH DOCK, Gourmet Kitchen, Pet and Family Friendly, Charming Coastal Camp~Pet Friendly, Deep Water Access: Jourdan/Gulf-Private Dock

Top trending hotels in Picayune

Holiday Inn Express Picayune-Stennis Space Center, an IHG Hotel

Holiday Inn Express Picayune-Stennis Space Center, an IHG Hotel

2.5 out of 5
1001 Dauphin Street, Picayune, MS
Fully refundable
The price is AU$174 per night from 2 Feb to 3 Feb
AU$174
includes taxes & fees
2 Feb - 3 Feb
With a stay at Holiday Inn Express Picayune-Stennis Space Center, an IHG Hotel in Picayune, you'll be within a 10-minute drive of Crosby Arboretum and Highland ...
Holiday Inn Express Picayune-Stennis Space Center, an IHG Hotel
Days Inn by Wyndham Picayune

Days Inn by Wyndham Picayune

2 out of 5
450 S Lofton Avenue, Picayune, MS
Fully refundableReserve now, pay when you stay
The price is AU$76 per night from 30 Jan to 31 Jan
AU$76
includes taxes & fees
30 Jan - 31 Jan
When you stay at Days Inn by Wyndham Picayune in Picayune, you'll be within a 10-minute drive of Crosby Arboretum and Highland Community Hospital.
Days Inn by Wyndham Picayune
Heritage Inn Picayune

Heritage Inn Picayune

2 out of 5
1122 Memorial Blvd., Picayune, MS
Fully refundableReserve now, pay when you stay
The price is AU$151 per night from 24 Jan to 25 Jan
AU$151
includes taxes & fees
24 Jan - 25 Jan
Located in Picayune, Heritage Inn Picayune is a 4-minute drive from Crosby Arboretum and 6 minutes from Highland Community Hospital.
Heritage Inn Picayune
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Hollywood Casino Gulf Coast

Hollywood Casino Gulf Coast

3.5 out of 5
711 Hollywood Blvd, Bay St Louis, MS
Fully refundableReserve now, pay when you stay
The price is AU$137 per night from 20 Jan to 21 Jan
AU$137
includes taxes & fees
20 Jan - 21 Jan
Located in Bay St Louis, Hollywood Casino Gulf Coast is near the bay, a 1-minute drive from Bridges Golf Club and 15 minutes from Buccaneer State Park.
Hollywood Casino Gulf Coast
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.