Book Holiday Homes in Santee

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Featured Holiday Homes in Santee

Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

4 out of 5
401 Bass Drive, Santee, SC
With a stay at Wyndham Vacation Resorts Lake Marion in Santee, you'll be within a 15-minute walk of Santee State Park and Santee Cooper Country Club.
Wyndham Vacation Resorts Lake Marion
Sweet Marion - Dock + Boat Ramp + Spa + Lakefront!

Sweet Marion - Dock + Boat Ramp + Spa + Lakefront!

Summerton
With a stay at this vacation home in Summerton, you'll be within a 15-minute walk of Taw Caw Creek and Foxboro Golf Club.
Sweet Marion - Dock + Boat Ramp + Spa + Lakefront!
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

Manning
Located in Manning, this vacation home is on the waterfront, within a 15-minute drive of Wyboo Golf Club and Potato Creek.
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
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Deep water Lake Marion house.  4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Summerton
Located in Summerton, this vacation home is on the waterfront, within a 15-minute drive of Lake Marion and Pine Island.
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Lakefront Retreat on Lake Marion

Lakefront Retreat on Lake Marion

Summerton
Located in Summerton, this vacation home is on the waterfront, within a 15-minute drive of Lake Marion and Pine Island.
Lakefront Retreat on Lake Marion
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Santee
Located in Santee, this vacation home is on a lake, a 4-minute drive from Santee Cooper Country Club and 6 minutes from Santee Outlets.
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Dukes Street Retreat 5min from I-95!

Dukes Street Retreat 5min from I-95!

Summerton
With a stay at this vacation home in Summerton, you'll be within a 15-minute drive of Potato Creek and Lake Marion.
Dukes Street Retreat 5min from I-95!
Cozy Lake House on Lake Marion with beautiful views of sunsets on the lake!

Cozy Lake House on Lake Marion with beautiful views of sunsets on the lake!

Manning
Located in Manning, this vacation home is within a 15-minute drive of Lake Marion and Wyboo Golf Club.
Cozy Lake House on Lake Marion with beautiful views of sunsets on the lake!
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

Summerton
Located in Summerton, this vacation home is on the waterfront, a 2-minute drive from Lake Marion and 9 minutes from Potato Creek.
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santee Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Santee vacation homes are the perfect way for you to wing it.

Holiday houses in Santee let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Santee in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Santee adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Santee with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Santee vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Santee Holiday Homes essential information

Accommodation
62 Holiday Homes
Lowest Price
AU$143
Highest Price
AU$233
Popular accommodation
Wyndham Vacation Resorts Lake Marion, Sweet Marion - Dock + Boat Ramp + Spa + Lakefront!, Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy, Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS, Lakefront Retreat on Lake Marion, Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!, Dukes Street Retreat 5min from I-95!, Cozy Lake House on Lake Marion with beautiful views of sunsets on the lake!, SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

Top trending hotels in Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$143 per night from 2 Feb to 3 Feb
AU$143
includes taxes & fees
2 Feb - 3 Feb
A stay at Baymont by Wyndham Santee places you in the heart of Santee, within a 5-minute drive of Santee Cooper Country Club and Santee National Golf Club.
Baymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$197 per night from 2 Feb to 3 Feb
AU$197
includes taxes & fees
2 Feb - 3 Feb
Located in Santee, Tru By Hilton Santee is within a 5-minute drive of Santee Cooper Country Club and Santee Outlets.
Tru By Hilton Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$233 per night from 2 Feb to 3 Feb
AU$233
includes taxes & fees
2 Feb - 3 Feb
With a stay at Fairfield Inn & Suites by Marriott Santee in Santee, you'll be a 1-minute walk from Santee Cooper Country Club and 12 minutes by foot from Santee ...
Fairfield Inn & Suites by Marriott Santee
Save an average of 15% on thousands of hotels when you're signed in
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$215 per night from 27 Jan to 28 Jan
AU$215
includes taxes & fees
27 Jan - 28 Jan
With a stay at Hampton Inn Santee-I-95 in Santee, you'll be near the airport, just a 1-minute walk from Santee Cooper Country Club and 11 minutes by foot from ...
Hampton Inn Santee-I-95
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.