Book Holiday Homes in Santee

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Featured Holiday Homes in Santee

Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion

4 out of 5
401 Bass Drive, Santee, SC
With a stay at Wyndham Vacation Resorts Lake Marion in Santee, you'll be within a 15-minute walk of Santee State Park and Santee Cooper Country Club.
Wyndham Vacation Resorts Lake Marion
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

Manning
Located in Manning, this vacation home is on the waterfront, within a 15-minute drive of Wyboo Golf Club and Potato Creek.
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
Deep water Lake Marion house.  4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Summerton
Located in Summerton, this vacation home is on the waterfront, within a 15-minute drive of Lake Marion and Pine Island.
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
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Beautiful lake home to make your family vacation extra special!

Beautiful lake home to make your family vacation extra special!

Summerton
Located in Summerton, this vacation home is in a rural location, a 1-minute drive from Lake Marion and 8 minutes from Potato Creek.
Beautiful lake home to make your family vacation extra special!
The Bunkhouse at St Julien - Vintage Waterfront Lake House

The Bunkhouse at St Julien - Vintage Waterfront Lake House

Eutawville
When you stay at this vacation home in Eutawville, you'll be on the waterfront and steps from Lake Marion.
The Bunkhouse at St Julien - Vintage Waterfront Lake House
Lake Marion Lakehouse with 180° lake view

Lake Marion Lakehouse with 180° lake view

Elloree
Located in Elloree, this vacation home is on the waterfront, within a 15-minute drive of Lake Marion and Orangeburg County Library Mentor Branch.
Lake Marion Lakehouse with 180° lake view
LAKE MARION LAKE FRONT VACATION RENTAL

LAKE MARION LAKE FRONT VACATION RENTAL

Manning
Located in Manning, this vacation home is on the waterfront, within a 15-minute drive of Wyboo Golf Club and Potato Creek.
LAKE MARION LAKE FRONT VACATION RENTAL
Archie's Lake Daze Cottage

Archie's Lake Daze Cottage

Manning
Located in Manning, this vacation home is on the waterfront, within a 15-minute drive of Lake Marion and Wyboo Golf Club.
Archie's Lake Daze Cottage
Dukes Street Retreat 5min from I-95!

Dukes Street Retreat 5min from I-95!

Summerton
With a stay at this vacation home in Summerton, you'll be within a 15-minute drive of Potato Creek and Lake Marion.
Dukes Street Retreat 5min from I-95!
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santee Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Santee vacation homes are the perfect way for you to wing it.

Holiday houses in Santee let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Santee in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Santee adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Santee with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Santee vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Santee Holiday Homes essential information

Accommodation
63 Holiday Homes
Lowest Price
AU$137
Highest Price
AU$243
Popular accommodation
Wyndham Vacation Resorts Lake Marion, Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy, Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS, Beautiful lake home to make your family vacation extra special!, The Bunkhouse at St Julien - Vintage Waterfront Lake House , Lake Marion Lakehouse with 180° lake view, LAKE MARION LAKE FRONT VACATION RENTAL, Archie's Lake Daze Cottage , Dukes Street Retreat 5min from I-95!

Top trending hotels in Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$137 per night from 26 Nov to 27 Nov
AU$137
includes taxes & fees
26 Nov - 27 Nov
A stay at Baymont by Wyndham Santee places you in the heart of Santee, within a 5-minute drive of Santee Cooper Country Club and Santee National Golf Club.
Baymont by Wyndham Santee
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$222 per night from 1 Dec to 2 Dec
AU$222
includes taxes & fees
1 Dec - 2 Dec
With a stay at Fairfield Inn & Suites by Marriott Santee in Santee, you'll be a 1-minute walk from Santee Cooper Country Club and 12 minutes by foot from Santee ...
Fairfield Inn & Suites by Marriott Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$243 per night from 4 Dec to 5 Dec
AU$243
includes taxes & fees
4 Dec - 5 Dec
With a stay at Hampton Inn Santee-I-95 in Santee, you'll be near the airport, just a 1-minute walk from Santee Cooper Country Club and 11 minutes by foot from ...
Hampton Inn Santee-I-95
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Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St., Santee, SC
Fully refundableReserve now, pay when you stay
The price is AU$188 per night from 3 Dec to 4 Dec
AU$188
includes taxes & fees
3 Dec - 4 Dec
Located in Santee, Tru By Hilton Santee is within a 5-minute drive of Santee Cooper Country Club and Santee Outlets.
Tru By Hilton Santee
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.