Book Holiday Homes in St. James

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in St. James

Vineyard Ridge Farmhouse

Vineyard Ridge Farmhouse

Saint James
The price is AU$371 per night from 4 May to 5 May
AU$371
includes taxes & fees
4 May - 5 May
When you stay at this vacation home in St. James, you'll be within a 10-minute drive of Rosati Winery Museum and Heinrichshaus Vineyard And Winery.
Vineyard Ridge Farmhouse
Cozy Modern Farmhouse that Sleeps 8

Cozy Modern Farmhouse that Sleeps 8

Rolla
Located in Rolla, this vacation home is within a 5-minute drive of Ponzer Park and Cedar Street Playhouse.
Cozy Modern Farmhouse that Sleeps 8
Seclusion in a beautiful setting where your dog can run free!

Seclusion in a beautiful setting where your dog can run free!

Owensville
With a stay at this vacation home in Owensville, you'll be on the waterfront, and 15.8 mi (25.4 km) from Heinrichshaus Vineyard And Winery and 17.4 mi (28 km) ...
Seclusion in a beautiful setting where your dog can run free!
Save an average of 15% on thousands of hotels when you're signed in
The James Stay on Historic Route 66, minutes away from Wineries & Restaurants

The James Stay on Historic Route 66, minutes away from Wineries & Restaurants

Saint James
The price is AU$306 per night from 24 Apr to 25 Apr
AU$306
includes taxes & fees
24 Apr - 25 Apr
With a stay at this vacation home in St. James, you'll be within a 5-minute drive of Meramec Vineyards and St. James Winery.
The James Stay on Historic Route 66, minutes away from Wineries & Restaurants
4BR, 2BA | Sleeps 8 | 5 Min to S&T & Downtown

4BR, 2BA | Sleeps 8 | 5 Min to S&T & Downtown

Rolla
The price is AU$360 per night from 27 Apr to 28 Apr
AU$360
includes taxes & fees
27 Apr - 28 Apr
Located in Rolla, this vacation home is within a 15-minute walk of Cedar Street Playhouse and Missouri University of Science and Technology.
4BR, 2BA | Sleeps 8 | 5 Min to S&T & Downtown
The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

Saint James
The price is AU$334 per night from 21 May to 22 May
AU$334
includes taxes & fees
21 May - 22 May
Located in St. James, this vacation home is within a 10-minute drive of Rosati Winery Museum and Heinrichshaus Vineyard And Winery.
The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James
Stylish 2Bdrm Bungalow | Walkable + Well Equipped

Stylish 2Bdrm Bungalow | Walkable + Well Equipped

Rolla
Located in Rolla, this vacation home is within a 15-minute walk of Cedar Street Playhouse and Regal Forum.
Stylish 2Bdrm Bungalow | Walkable + Well Equipped
Scenic Lakeside Chateau with Heated Pool, Hot Tub & Outdoor Kitchen-TV-Fireplace

Scenic Lakeside Chateau with Heated Pool, Hot Tub & Outdoor Kitchen-TV-Fireplace

Belle
With a stay at this vacation home in Belle, you'll be on the waterfront, and 14.1 mi (22.6 km) from Wenwood Farm Winery and 14.6 mi (23.5 km) from Osage County ...
Scenic Lakeside Chateau with Heated Pool, Hot Tub & Outdoor Kitchen-TV-Fireplace
Luxury Home in Woods w/ Easy Access to Large Private Gravel Bar on Meramec River

Luxury Home in Woods w/ Easy Access to Large Private Gravel Bar on Meramec River

Steelville
Located in Steelville, this vacation home is on the waterfront, within a 15-minute drive of Meramec River and Mark Twain National Forest.
Luxury Home in Woods w/ Easy Access to Large Private Gravel Bar on Meramec River
Don't see what you're looking for?
See all available properties in St. James
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. James Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our St. James vacation homes are the perfect way for you to wing it.

Holiday houses in St. James let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of St. James in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local St. James adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in St. James with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of St. James vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

St. James Holiday Homes essential information

Accommodation
71 Holiday Homes
Lowest Price
AU$85
Highest Price
AU$371
Popular accommodation
Vineyard Ridge Farmhouse , Cozy Modern Farmhouse that Sleeps 8, Seclusion in a beautiful setting where your dog can run free!, The James Stay on Historic Route 66, minutes away from Wineries & Restaurants, 4BR, 2BA | Sleeps 8 | 5 Min to S&T & Downtown, The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James , Stylish 2Bdrm Bungalow | Walkable + Well Equipped, Scenic Lakeside Chateau with Heated Pool, Hot Tub & Outdoor Kitchen-TV-Fireplace, Luxury Home in Woods w/ Easy Access to Large Private Gravel Bar on Meramec River

Top trending hotels in St. James

Greenlight Inn & Suites

Greenlight Inn & Suites

2 out of 5
110 N Outer Rd, St. James, MO
Fully refundableReserve now, pay when you stay
The price is AU$109 per night from 3 May to 4 May
AU$109
includes taxes & fees
3 May - 4 May
A stay at Greenlight Inn & Suites places you in the heart of St. James, within a 5-minute drive of St. James Winery and Meramec Vineyards.
Greenlight Inn & Suites
Economy Inn

Economy Inn

2.5 out of 5
102 N Outer Rd, St. James, MO
Fully refundableReserve now, pay when you stay
The price is AU$85 per night from 21 Apr to 22 Apr
AU$85
includes taxes & fees
21 Apr - 22 Apr
Located in St. James, Economy Inn is within a 5-minute drive of St. James Winery and Meramec Vineyards.
Economy Inn
Finns Motel

Finns Motel

2.5 out of 5
777 Grover St, St. James, MO
The price is AU$98 per night from 21 Apr to 22 Apr
AU$98
includes taxes & fees
21 Apr - 22 Apr
With a stay at Finns Motel in St. James, you'll be within a 5-minute drive of St. James Winery and Meramec Vineyards.
Finns Motel
Save an average of 15% on thousands of hotels when you're signed in
Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.

Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.

Saint James
The price is AU$283 per night from 22 Apr to 23 Apr
AU$283
includes taxes & fees
22 Apr - 23 Apr
With a stay at this cottage in St. James, you'll be within a 5-minute drive of St. James Winery and Meramec Vineyards.
Cozy Cottage on Historic Route 66, minutes away from Wineries & Restaurants.
Don't see what you're looking for?
See all available properties in St. James
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.