21C Museum Hotel St Louis

4.5 star property

Photo gallery for 21C Museum Hotel St Louis

Exterior
Room, 1 King Bed, Corner
Lobby
In-room safe, desk, laptop workspace, blackout curtains
Indoor pool

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Bar

Explore the area

Map
1528 Locust street, St. Louis, MO, 63103
  • Enterprise Center
    ‪8 min walk‬
  • St. Louis Union Station
    ‪12 min walk‬
  • Busch Stadium
    ‪18 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪26 min drive‬

Room options

Loft, 2 Queen Beds

  • Sleeps 4
  • 2 Queen Beds

Room (Bunk Bed)

  • Sleeps 2
  • 1 Twin Bunk Bed

Deluxe Room, Accessible (Accessible)

  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

  • Sleeps 4
  • 1 Double Bed

Deluxe Room, 1 King Bed

  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

  • Sleeps 2
  • 1 Double Bed

Deluxe Double Room, 2 Queen Beds

  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

  • Sleeps 4
  • 1 Double Bed

Room, 1 King Bed, Corner

  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

Luxury Double Room, 2 Queen Beds

  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

Similar properties

About the area

St. Louis

A stay at 21C Museum Hotel St Louis places you in the heart of St. Louis, within a 10-minute walk of Enterprise Center and City Museum. .This luxury hotel is 0.6 mi (1 km) from St. Louis Union Station and 0.7 mi (1.1 km) from America's Center Convention Complex.

What's nearby

  • City Museum - 6 min walk - 0.6 km
  • Enterprise Center - 8 min walk - 0.7 km
  • St. Louis Union Station - 12 min walk - 1.0 km
  • Busch Stadium - 18 min walk - 1.6 km
  • Gateway Arch - 4 min drive - 2.7 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • St. Louis Lambert Intl. Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel with a fitness center and a steam room
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool, a steam room, and a fitness center.
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
Make yourself at home in one of the 104 air-conditioned rooms featuring espresso makers and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include phones, as well as safes and desks.
Don't miss out on the many recreational opportunities, including an indoor pool, a steam room, and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and a banquet hall.
Enjoy a meal at the restaurant or snacks in the coffee shop/cafe. The hotel also offers room service (during limited hours). Wrap up your day with a drink at the bar/lounge. Cooked-to-order breakfasts are available daily from 6:30 AM to 1:00 PM for a fee.
Featured amenities include a business center, dry cleaning/laundry services, and a 24-hour front desk.
Cooked-to-order breakfasts are available for a surcharge and are served each morning between 6:30 AM and 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Languages

English

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 796 out of 1099 reviews
Rating 8 - Good. 170 out of 1099 reviews
Rating 6 - Okay. 61 out of 1099 reviews
Rating 4 - Poor. 32 out of 1099 reviews
Rating 2 - Terrible. 40 out of 1099 reviews

9.4/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Savannah

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Went for my birthday weekend and enjoyed every amenity! There is quite no other hotel Ive been to where it had something to enjoy for anytime of the day. Whether it was the good press cafe in the morning, a midday swim, a good cocktail from idol wolf, or a lookaloo around the free art museum on the 2nd floor or even a good exercise. The room was phenomenal with a great view of downtown stl!
Stayed 2 nights in Jan 2025

10/10 Excellent

Raven

Liked: Cleanliness, staff & service, property conditions & facilities
It was such cool place! The pool and spa were so fun and Good Press was great for breakfast.
Stayed 2 nights in Jan 2025

10/10 Excellent

Todd, Lake St Louis

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Jan 2025

8/10 Good

Monir

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Love the look and people!!
Stayed 2 nights in Dec 2024

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

4/10 Poor

Audrey

Travelled with group
Disliked: Cleanliness, property conditions & facilities
First checked in for my birthday weekend and they didn’t have my room ready until 8:30 PM when check in was at 4. They put us in a temporary room which was a room for one person when we had 4 and which had not been cleaned and other items of other peoples stuff were in there. Only stayed for one night and it ruined the whole reason of a doing a girls night in stl. The front desk was very honest so I appreciated that but she thought I was someone that she checked in and had an attitude at the beginning and I had to let her know that she needed to look up my account before assuming who I was. This was for my birthday and I thought this was going to be the best night but the staff and hotel just made it such a horrible experience for me. I actually started crying with the way they did everything. Just super disappointed because with the right staff and training this hotel could easily be 5 star hotel. I do want to put in here though that the valet parking crew was incredibly nice though and seem to really care.
Stayed 1 night in Jan 2025

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities
We stayed here after the Kody Johnson concert. Quick, convenient walk.
Stayed 1 night in Jan 2025

8/10 Good

Kenneth, Normal

Stayed 1 night in Jan 2025

10/10 Excellent

Bryan Rachel Caughran

Travelled with partner
Liked: Cleanliness, staff & service, property conditions & facilities
Outstanding place, just need a vending machine for snacks.
Stayed 1 night in Jan 2025

10/10 Excellent

Bailey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Convenient & Clean

Beautiful hotel with a perfect location! Staff was very friendly and vallet was so fast!
Stayed 1 night in Jan 2025

10/10 Excellent

Tylyn

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Super nive4 place little pricy for food but the food is worth it and love the museum and the drinks again a little pricy but is a great time and the staff are so friendly.
Stayed 1 night in Nov 2024

10/10 Excellent

CRISTINA

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Jan 2025

8/10 Good

David

Liked: Cleanliness
Stayed 5 nights in Jan 2025

10/10 Excellent

Leslie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

perfect for couples

We stayed at 21C for an overnight getaway. The check in was seamless- the staff was very friendly. Our room was beautiful and clean (was missing body wash but it was quickly rectified). The robes were luxurious, a really nice touch. We enjoyed all of the amenities at the hotel; the pool, hot tub and sauna (all clean and enjoyable), the "nightcap at the museum" and the art museum as well. We had a reservation at the restaurant (best burger in town!) and went back to the bar for dessert and drinks later in the evening (I wish dessert was better). In the morning we went to the coffee shop for breakfast (so delicious!). Everything we needed was right there. The only negatives were; the pillows were not comfortable, the cups in the room for coffee were disposable and not mugs (I prefer mugs and that's what's shown on the website) and I wish parking wasn't so expensive. Overall, a really wonderful experience- we will definitely stay at the 21C again.
Stayed 1 night in Jan 2025

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Stay here instead of a conference hotel!

Lovely two-night stay at the 21c STL. Very reasonable room price, nice bar and very good restaurant, comfy "gameroom" for hanging out. Thoughtful art and interior design as you would expect from a 21c property. Yummy coffee/tea/breakfast shop.
Stayed 2 nights in Jan 2025

8/10 Good

Josh

Stayed 1 night in Jan 2025

8/10 Good

Ana Cecilia Correia

Business traveller
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
More museum than hotel, food options limited and very busy main floor and restaurant
Stayed 6 nights in Dec 2024

10/10 Excellent

Michael

Travelled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Cool spot
Stayed 2 nights in Jan 2025

10/10 Excellent

Kevin, Leawood

Travelled with pets, Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
A Perfectly Curated Wes Anderson-Style Stay at 21c Museum Hotel St. Louis The 21c Museum Hotel in St. Louis is nothing short of extraordinary—a perfectly curated Wes Anderson-esque experience that feels as if you’ve stepped into a cinematic dream. From the moment we arrived, we were immersed in the hotel’s vibrant yet sophisticated aesthetic, seamlessly blending artistry and luxury. Our corner suite was a highlight, featuring impeccable design and one of the most stunning bathrooms we’ve ever seen. Every detail, from the decor to the amenities, exuded thoughtful elegance. The spacious layout and expansive views made it a true haven of relaxation. The hotel’s dedication to merging art and hospitality sets it apart. Wandering through the gallery-like spaces was a delightful experience, with each piece adding to the hotel’s unique charm. The staff was attentive and welcoming, ensuring our stay was flawless from start to finish. This was, without a doubt, one of the finest hotels we’ve ever stayed at. We are eagerly anticipating our return, this time to indulge in the duplex 21c Suite, which promises an even more extraordinary stay. For anyone seeking an unforgettable blend of art, design, and luxury, the 21c Museum Hotel St. Louis is an absolute must-visit.

10/10 Excellent

KELLIE

Stayed 1 night in Dec 2024

10/10 Excellent

Staci

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Dec 2024

8/10 Good

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

John

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
How friendly the velet parking people were. Didnt really car for it being a lane pool and how expiedia stated the rooms were sound proof when they were not. But other than that it was an amazing stay!
Stayed 2 nights in Jan 2025

10/10 Excellent

Becky

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfection!

10 out of 10. This will be our new STL staycation when we need a night away. Restaurant was fabulous - food drinks and service all outstanding - then strolled thru the museum for some culture with a drink bf calling it a night. Next time would love to enjoy the pool, hot tub and spa!
Stayed 1 night in Jan 2025