Book Holiday Homes in Wykoff

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in Wykoff

Century Cottage-PERFECT for Mayo & downtown visitors!

Century Cottage-PERFECT for Mayo & downtown visitors!

Rochester
With a stay at this vacation home, you'll be centrally located in Rochester, within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys ...
Century Cottage-PERFECT for Mayo & downtown visitors!
Park in the Garage and Walk to Mayo Clinic

Park in the Garage and Walk to Mayo Clinic

Rochester
With a stay at this vacation home in Rochester (Northrup), you'll be within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus.
Park in the Garage and Walk to Mayo Clinic
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

Rochester
A stay at this vacation home places you in the heart of Rochester, within a 15-minute walk of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus.
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Save an average of 15% on thousands of hotels when you're signed in
Coratel Inn & Suites by Jasper Rochester-2 Queen Bed Non Smoking

Coratel Inn & Suites by Jasper Rochester-2 Queen Bed Non Smoking

Rochester
The price is AU$167 per night from 24 Dec to 25 Dec
AU$167
includes taxes & fees
24 Dec - 25 Dec
With a stay at this vacation home in Rochester, you'll be within a 10-minute drive of Mayo Clinic Hospital - Saint Marys Campus and Mayo Clinic.
Coratel Inn & Suites by Jasper Rochester-2 Queen Bed Non Smoking
City Hall Recorder's Office

City Hall Recorder's Office

2 out of 5
Rochester
Located in Rochester (Downtown Rochester), this vacation home is within a 15-minute walk of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus.
City Hall Recorder's Office
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆

☆Dee Dee's Den: A Dharma Dwellings Parent Company☆

Rochester
With a stay at this vacation home, you'll be centrally located in Rochester, a 4-minute drive from Mayo Clinic and 6 minutes from Mayo Clinic Hospital - Saint ...
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard

Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard

Rochester
The price is AU$500 per night from 26 Dec to 27 Dec
AU$500
includes taxes & fees
26 Dec - 27 Dec
With a stay at this vacation home in Rochester (Northrup), you'll be within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus.
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
Fresh space near Mayo Clinic and downtown

Fresh space near Mayo Clinic and downtown

Rochester
With a stay at this vacation home in Rochester (Slatterly Park), you'll be within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys ...
Fresh space near Mayo Clinic and downtown
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly

Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly

Rochester
With a stay at this vacation home in Rochester (Slatterly Park), you'll be within a 5-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys ...
Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly
Don't see what you're looking for?
See all available properties in Wykoff
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Wykoff Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Wykoff vacation homes are the perfect way for you to wing it.

Holiday houses in Wykoff let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Wykoff in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Wykoff adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Wykoff with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Wykoff vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Wykoff Holiday Homes essential information

Accommodation
116 Holiday Homes
Lowest Price
AU$136
Highest Price
AU$500
Popular accommodation
Century Cottage-PERFECT for Mayo & downtown visitors!, Park in the Garage and Walk to Mayo Clinic, Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown., Coratel Inn & Suites by Jasper Rochester-2 Queen Bed Non Smoking, City Hall Recorder's Office, ☆Dee Dee's Den: A Dharma Dwellings Parent Company☆, Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard, Fresh space near Mayo Clinic and downtown, Park-Side, Easy Access To Downtown, Mayo Clinic & Bike Trail, Family-Friendly

Top trending hotels in Wykoff

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is AU$274 per night from 24 Dec to 25 Dec
AU$274
includes taxes & fees
24 Dec - 25 Dec
A stay at Kahler Grand Hotel places you in the heart of Rochester, within a 5-minute walk of Mayo Clinic and University of Minnesota-Rochester.
Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is AU$136 per night from 27 Dec to 28 Dec
AU$136
includes taxes & fees
27 Dec - 28 Dec
When you stay at AmericInn by Wyndham Rochester Near Mayo Clinic in Rochester, you'll be in a shopping district, within a 5-minute drive of Olmsted County Fairgrounds ...
AmericInn by Wyndham Rochester Near Mayo Clinic
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is AU$148 per night from 24 Dec to 25 Dec
AU$148
includes taxes & fees
24 Dec - 25 Dec
With a stay at Med City Inn & Suites - Mayo Clinic Area, you'll be centrally located in Rochester, within a 5-minute drive of Mayo Clinic Hospital - Saint Marys ...
Med City Inn & Suites - Mayo Clinic Area
Save an average of 15% on thousands of hotels when you're signed in
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is AU$256 per night from 24 Dec to 25 Dec
AU$256
includes taxes & fees
24 Dec - 25 Dec
Kahler Inn and Suites - Mayo Clinic Area is centrally located in Rochester, a 3-minute walk from Mayo Clinic and 7 minutes by foot from University of ...
Kahler Inn and Suites - Mayo Clinic Area
Don't see what you're looking for?
See all available properties in Wykoff
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.