Book Holiday Homes in De Soto

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Featured Holiday Homes in De Soto

Newly remodeled cozy retreat. Pet friendly & 3 minute walk to the river!

Newly remodeled cozy retreat. Pet friendly & 3 minute walk to the river!

Lynxville
The price is AU$197 per night from 25 Dec to 26 Dec
AU$197
includes taxes & fees
25 Dec - 26 Dec
When you stay at this vacation home in Eastman, you'll be 5 minutes by foot from Mississippi River.
Newly remodeled cozy retreat. Pet friendly & 3 minute walk to the river!
This big old charming house Viroqua

This big old charming house Viroqua

Viroqua
Located in Viroqua, this vacation home is within a 5-minute drive of Fortney Underground Theater and Vernon Memorial Healthcare.
This big old charming house Viroqua
Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

Brownsville
When you stay at this vacation home in Brownsville, you'll be on the waterfront and 6 minutes by foot from Mississippi River.
Secluded Home - Views of Mississippi River remote location 15 min from La Crosse
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Wisconsin's Driftless Region Retreat

Wisconsin's Driftless Region Retreat

Viroqua
Located in Viroqua, this vacation home is in a rural location, within a 10-minute drive of Viroqua Clinic and Viroqua Country Club.
Wisconsin's Driftless Region Retreat
Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.

Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.

Stoddard
When you stay at this vacation home in Coon Valley, you'll be 13 minutes by car from Shrine of our Lady of Guadalupe.
Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.
Riverfront Twin Home

Riverfront Twin Home

La Crosse
The price is AU$532 per night from 1 Jan to 2 Jan
AU$532
includes taxes & fees
1 Jan - 2 Jan 2025
Located in La Crosse, this vacation home is within a 15-minute walk of Mississippi River and Gundersen Health System - La Crosse Medical Center.
Riverfront Twin Home
3-bedroom country home in the driftless.

3-bedroom country home in the driftless.

Westby
Located in Westby, this vacation home is within a 15-minute drive of Vernon Vineyards and Branches Winery.
3-bedroom country home in the driftless.
Tiny House on Upper Iowa River w/ hot tub

Tiny House on Upper Iowa River w/ hot tub

dorchester
The price is AU$330 per night from 2 Jan to 3 Jan
AU$330
includes taxes & fees
2 Jan - 3 Jan 2025
With a stay at this vacation home in Dorchester, you'll be 12.6 mi (20.3 km) from Locust School and 15.9 mi (25.6 km) from Bluff Country Artists Gallery.
Tiny House on Upper Iowa River w/ hot tub
Premium 3BR 3BA with Hot Tub & Pool, near all of LaCrosse's Top Rated Activities

Premium 3BR 3BA with Hot Tub & Pool, near all of LaCrosse's Top Rated Activities

La Crosse
Located in La Crosse, this vacation home is on a river, a 4-minute drive from Mount La Crosse Ski Area and 5 minutes from Shrine of our Lady of Guadalupe.
Premium 3BR 3BA with Hot Tub & Pool, near all of LaCrosse's Top Rated Activities
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

De Soto Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our De Soto vacation homes are the perfect way for you to wing it.

Holiday houses in De Soto let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of De Soto in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local De Soto adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in De Soto with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of De Soto vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

De Soto Holiday Homes essential information

Accommodation
72 Holiday Homes
Lowest Price
AU$197
Highest Price
AU$603
Popular accommodation
Newly remodeled cozy retreat. Pet friendly & 3 minute walk to the river!, This big old charming house Viroqua, Secluded Home - Views of Mississippi River remote location 15 min from La Crosse, Wisconsin's Driftless Region Retreat, Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley., Riverfront Twin Home , 3-bedroom country home in the driftless. , Tiny House on Upper Iowa River w/ hot tub, Premium 3BR 3BA with Hot Tub & Pool, near all of LaCrosse's Top Rated Activities

Top trending hotels in De Soto

Rustic Hideaway Sleeps 4 HOT TUB

Rustic Hideaway Sleeps 4 HOT TUB

De Soto
The price is AU$603 per night from 5 Jan to 6 Jan
AU$603
includes taxes & fees
5 Jan - 6 Jan 2025
When you stay at this cabin in De Soto, you'll be on a river and 11 minutes by car from Mississippi River.
Rustic Hideaway Sleeps 4 HOT TUB
Cozy Sportsman's Hideaway

Cozy Sportsman's Hideaway

De Soto
When you stay at this cabin in De Soto, you'll be 14 minutes by car from Mississippi River.
Cozy Sportsman's Hideaway
Paradise Point- Sleeps 4 HOT TUB

Paradise Point- Sleeps 4 HOT TUB

De Soto
The price is AU$563 per night from 5 Jan to 6 Jan
AU$563
includes taxes & fees
5 Jan - 6 Jan 2025
When you stay at this cabin in De Soto, you'll be on the waterfront and 11 minutes by car from Mississippi River.
Paradise Point- Sleeps 4 HOT TUB
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Majestic View Sleeps 10-HOT TUB

Majestic View Sleeps 10-HOT TUB

De Soto
When you stay at this vacation home in De Soto, you'll be on a river and 10 minutes by car from Mississippi River.
Majestic View Sleeps 10-HOT TUB
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See all available properties in De Soto
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.