Book Holiday Homes in De Soto

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Featured Holiday Homes in De Soto

This big old charming house Viroqua

This big old charming house Viroqua

Viroqua
Located in Viroqua, this vacation home is within a 5-minute drive of Fortney Underground Theater and Vernon Memorial Healthcare.
This big old charming house Viroqua
Mississippi waterfront vacation home that welcomes dogs! Private dock for boats

Mississippi waterfront vacation home that welcomes dogs! Private dock for boats

2 out of 5
Brownsville
When you stay at this vacation home in Brownsville, you'll be 1 minutes by foot from Mississippi River.
Mississippi waterfront vacation home that welcomes dogs! Private dock for boats
Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.

Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.

Stoddard
When you stay at this vacation home in Coon Valley, you'll be 13 minutes by car from Shrine of our Lady of Guadalupe.
Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley.
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Indoor Fish Cleaning - Arcade - Darts - Poker - Newly Remodeled

Indoor Fish Cleaning - Arcade - Darts - Poker - Newly Remodeled

Genoa
With a stay at this vacation home in Genoa, you'll be on a river, within a 10-minute drive of Mississippi River and Romance Prairie State Natural Area.
Indoor Fish Cleaning - Arcade - Darts - Poker - Newly Remodeled
Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

Secluded Home - Views of Mississippi River remote location 15 min from La Crosse

Brownsville
With a stay at this vacation home in Brownsville, you'll be on the waterfront and 6 minutes by foot from Mississippi River.
Secluded Home - Views of Mississippi River remote location 15 min from La Crosse
Spacious Stoddard Retreat on Mississippi River!

Spacious Stoddard Retreat on Mississippi River!

Stoddard
Located in Stoddard, this vacation home is on the waterfront, within a 15-minute drive of Mount La Crosse Ski Area and Shrine of our Lady of Guadalupe.
Spacious Stoddard Retreat on Mississippi River!
Large Secluded Country Home Minutes from Town

Large Secluded Country Home Minutes from Town

La Crosse
With a stay at this vacation home in La Crosse, you'll be within a 15-minute drive of Shrine of our Lady of Guadalupe and Mount La Crosse Ski Area.
Large Secluded Country Home Minutes from Town
Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!

Eastman
The price is AU$300 per night from 23 Feb to 24 Feb
AU$300
includes taxes & fees
23 Feb - 24 Feb
With a stay at this vacation home in Eastman, you'll be on a river, within a 10-minute drive of Mississippi River and Lynxville Library.
Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!
Tiny House on Upper Iowa River w/ hot tub

Tiny House on Upper Iowa River w/ hot tub

dorchester
With a stay at this vacation home in Dorchester, you'll be 12.6 mi (20.3 km) from Locust School and 15.9 mi (25.6 km) from Bluff Country Artists Gallery.
Tiny House on Upper Iowa River w/ hot tub
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

De Soto Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our De Soto vacation homes are the perfect way for you to wing it.

Holiday houses in De Soto let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of De Soto in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local De Soto adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in De Soto with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of De Soto vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

De Soto Holiday Homes essential information

Accommodation
72 Holiday Homes
Lowest Price
AU$300
Highest Price
AU$591
Popular accommodation
This big old charming house Viroqua, Mississippi waterfront vacation home that welcomes dogs! Private dock for boats, Secluded, Romantic, Family Friendly And Cozy, Last House In The Valley., Indoor Fish Cleaning - Arcade - Darts - Poker - Newly Remodeled , Secluded Home - Views of Mississippi River remote location 15 min from La Crosse, Spacious Stoddard Retreat on Mississippi River!, Large Secluded Country Home Minutes from Town, Hydro-Massage Tub! Wrangler Outlaw Suite! Horses!, Tiny House on Upper Iowa River w/ hot tub

Top trending hotels in De Soto

Paradise Point- Sleeps 4 HOT TUB

Paradise Point- Sleeps 4 HOT TUB

De Soto
The price is AU$549 per night from 24 Feb to 25 Feb
AU$549
includes taxes & fees
24 Feb - 25 Feb
When you stay at this cabin in De Soto, you'll be on the waterfront and 11 minutes by car from Mississippi River.
Paradise Point- Sleeps 4 HOT TUB
Cozy Ridge Retreat

Cozy Ridge Retreat

De Soto
With a stay at this cabin in De Soto, you'll be within a 15-minute drive of Mississippi River and Museum of River History.
Cozy Ridge Retreat
Cozy 3-bedroom cabin - sleeps 10- HOT TUB- river view

Cozy 3-bedroom cabin - sleeps 10- HOT TUB- river view

2 out of 5
De Soto
The price is AU$360 per night from 5 Mar to 6 Mar
AU$360
includes taxes & fees
5 Mar - 6 Mar
Located in De Soto, this cabin is within a 5-minute drive of Mount Hosmer Park and Museum of River History.
Cozy 3-bedroom cabin - sleeps 10- HOT TUB- river view
Save an average of 15% on thousands of hotels when you're signed in
Rustic Hideaway Sleeps 4 HOT TUB

Rustic Hideaway Sleeps 4 HOT TUB

De Soto
The price is AU$591 per night from 23 Feb to 24 Feb
AU$591
includes taxes & fees
23 Feb - 24 Feb
When you stay at this cabin in De Soto, you'll be on a river and 11 minutes by car from Mississippi River.
Rustic Hideaway Sleeps 4 HOT TUB
Don't see what you're looking for?
See all available properties in De Soto
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.