Book Holiday Homes in Isla Grande

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Featured Holiday Homes in Isla Grande

Spacious Beach House on the ocean front with huge pool and patio.

Spacious Beach House on the ocean front with huge pool and patio.

Republic de Panama - Guanche - Colon - P
Located in Mechi, this vacation home is by the ocean, a 4-minute drive from Playa La Angosta and 8 minutes from Portobelo National Park.
Spacious Beach House on the ocean front with huge pool and patio.
Cabaña La Punta op het Strand!!

Cabaña La Punta op het Strand!!

Colón Province
The price is AU$275 per night from 20 Feb to 21 Feb
AU$275
includes taxes & fees
20 Feb - 21 Feb
This vacation home is within the vicinity of Isla Mamey and Portobelo National Park.
Cabaña La Punta op het Strand!!
Casa Anzuelo is an oceanfront home that is all about the water and nature.

Casa Anzuelo is an oceanfront home that is all about the water and nature.

Portobelo
This vacation home is 0.1 mi (0.1 km) from Blanca Beach and 2.7 mi (4.4 km) from Isla Mamey.
Casa Anzuelo is an oceanfront home that is all about the water and nature.
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Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

Portobelo
The price is AU$623 per night from 7 Feb to 8 Feb
AU$623
includes taxes & fees
7 Feb - 8 Feb
With a stay at this vacation home in Portobelo, you'll be just steps from Real Aduana de Portobelo and Fuerte San Jerónimo.
Casa Dinis - Loft - CON Vistas Bahia DE Portobelo
Casa Frente al Mar - Isla Grande

Casa Frente al Mar - Isla Grande

Provincia de Colón
This vacation home is 5.3 mi (8.5 km) from Isla Mamey and 8 mi (12.9 km) from Blanca Beach.
Casa Frente al Mar - Isla Grande
Casa Dinis - Casa Grande - Centro DE Portobelo

Casa Dinis - Casa Grande - Centro DE Portobelo

Portobelo
The price is AU$956 per night from 7 Feb to 8 Feb
AU$956
includes taxes & fees
7 Feb - 8 Feb
With a stay at this vacation home in Portobelo, you'll be just steps from Real Aduana de Portobelo and Fuerte San Jerónimo.
Casa Dinis - Casa Grande - Centro DE Portobelo
Caribbean Paradise - Beachfront Getaway

Caribbean Paradise - Beachfront Getaway

Palenque
The price is AU$792 per night from 4 Mar to 5 Mar
AU$792
includes taxes & fees
4 Mar - 5 Mar
This vacation home is within the region of Portobelo National Park and Isla Mamey.
Caribbean Paradise - Beachfront Getaway
Despierta sobre el mar

Despierta sobre el mar

2 out of 5
Garrote
With a stay at this vacation home in Puerto Lindo, you'll be within a 15-minute drive of Isla Mamey and Portobelo National Park.
Despierta sobre el mar
Nice house in Portobelo, Skybluebyguanche

Nice house in Portobelo, Skybluebyguanche

Portobelo
The price is AU$250 per night from 20 Feb to 21 Feb
AU$250
includes taxes & fees
20 Feb - 21 Feb
Located in Mechi, this vacation home is a 2-minute drive from Portobelo National Park and 7 minutes from Fuerte Santiago.
Nice house in Portobelo, Skybluebyguanche
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Isla Grande Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Isla Grande vacation homes are the perfect way for you to wing it.

Holiday houses in Isla Grande let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Isla Grande in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Isla Grande adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Isla Grande with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Isla Grande vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Isla Grande Holiday Homes essential information

Accommodation
21 Holiday Homes
Lowest Price
AU$250
Highest Price
AU$1,575
Popular accommodation
Spacious Beach House on the ocean front with huge pool and patio., Cabaña La Punta op het Strand!!, Casa Anzuelo is an oceanfront home that is all about the water and nature., Casa Dinis - Loft - CON Vistas Bahia DE Portobelo, Casa Frente al Mar - Isla Grande, Casa Dinis - Casa Grande - Centro DE Portobelo, Caribbean Paradise - Beachfront Getaway, Despierta sobre el mar , Nice house in Portobelo, Skybluebyguanche

Top trending hotels in Isla Grande

Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande, Isla Grande, Colon
The price is AU$1,575 per night from 16 Feb to 17 Feb
AU$1,575
includes taxes & fees
16 Feb - 17 Feb
With a stay at Ordovician Beach Resort in Isla Grande, you'll be in a national park and close to Isla Mamey.
Ordovician Beach Resort
Coconut Grove Lodge

Coconut Grove Lodge

2.5 out of 5
North Coast, Isla Grande, Colon
With a stay at Coconut Grove Lodge in Isla Grande, you'll be on the beach and close to Isla Mamey.
Coconut Grove Lodge
Sister Moon Hotel

Sister Moon Hotel

2 out of 5
Punta del Este, Isla Grande
When you stay at Sister Moon Hotel in Isla Grande, you'll be on the beach and 13 minutes by car from Isla Mamey.
Sister Moon Hotel
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Brother Sun Villas

Brother Sun Villas

3 out of 5
Camino Al Faro, Isla Grande
When you stay at Brother Sun Villas in Isla Grande, you'll be on the beach and 13 minutes by car from Isla Mamey.
Brother Sun Villas
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.