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Featured Holiday Homes in Panama

Surfari Bocas

Surfari Bocas

2.5 out of 5
Avenida B entre Calle 4 y 5, Bocas del Toro, Bocas del Toro
The price is AU$58 per night from 10 Apr to 11 Apr
AU$58
includes taxes & fees
10 Apr - 11 Apr
A stay at Surfari Bocas places you in the heart of Bocas del Toro, steps from Bocas del Toro Ferry Terminal and 5 minutes by foot from Bolivar Park.
Surfari Bocas
Casa de Campo Mia

Casa de Campo Mia

2.5 out of 5
Calle 3 Sur, Nueva Gorgona, Panama
Located in Nueva Gorgona, Casa de Campo Mia is on the boardwalk/promenade, within a 15-minute drive of Coronado Mall and Playa Malibú.
Casa de Campo Mia
Apartamento en el Corazón de Boquete

Apartamento en el Corazón de Boquete

Boquete
With a stay at this vacation home in Boquete, you'll be within a 5-minute drive of Boquete Library and Schumann's Park.
Apartamento en el Corazón de Boquete
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Brand NEW Home Over on the Water

Brand NEW Home Over on the Water

Bocas del Toro
The price is AU$204 per night from 28 Mar to 29 Mar
AU$204
includes taxes & fees
28 Mar - 29 Mar
Located in Bocas del Toro, this vacation home is by the ocean, within a 15-minute walk of Lil' Spa Shop by the Sea and Playa El Istmito.
Brand NEW Home Over on the Water
Breathtaking Views Mansion w/King Beds

Breathtaking Views Mansion w/King Beds

Panamá
The price is AU$967 per night from 1 Apr to 2 Apr
AU$967
includes taxes & fees
1 Apr - 2 Apr
With a stay at this vacation home in Panama City (Bethania), you'll be within a 5-minute drive of Avenida Balboa and Via Espana.
Breathtaking Views Mansion w/King Beds
Bocas Villas - Private Acqua Villas

Bocas Villas - Private Acqua Villas

Bocas del Toro
Located in Bocas del Toro, this vacation home is by the ocean, within a 15-minute drive of Bocas Marina and Hospital Point.
Bocas Villas - Private Acqua Villas
Casita del Mar, Bocas del Toro, Panama

Casita del Mar, Bocas del Toro, Panama

Bocas del Toro
With a stay at this vacation home in Bocatorito, you'll be on the waterfront, and 15.1 mi (24.3 km) from Bluff Beach and 15.1 mi (24.3 km) from Paunch ...
Casita del Mar, Bocas del Toro, Panama
Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces

Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces

2 out of 5
Panamá
The price is AU$1,028 per night from 28 Mar to 29 Mar
AU$1,028
includes taxes & fees
28 Mar - 29 Mar
With a stay at this vacation home in Panama City, you'll be a 3-minute drive from Albrook Shopping Mall and 5 minutes from Avenida Balboa.
Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces
Casa Clearwater... Your Caribbean Dream

Casa Clearwater... Your Caribbean Dream

Bocas del Toro
This vacation home is 2.4 mi (3.9 km) from Tortuga Beach and 2.8 mi (4.5 km) from Playa El Istmito.
Casa Clearwater... Your Caribbean Dream
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Panama Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Panama vacation homes are the perfect way for you to wing it.

Holiday houses in Panama let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Panama in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Panama adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Panama with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Panama vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Panama Holiday Homes essential information

Accommodation
436 Holiday Homes
Lowest Price
AU$58
Highest Price
AU$1,028
Popular accommodation
Surfari Bocas, Casa de Campo Mia, Apartamento en el Corazón de Boquete, Brand NEW Home Over on the Water, Breathtaking Views Mansion w/King Beds, Bocas Villas - Private Acqua Villas , Casita del Mar, Bocas del Toro, Panama , Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces, Casa Clearwater... Your Caribbean Dream

Top trending hotels in Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AU$208 per night from 21 Apr to 22 Apr
AU$208
includes taxes & fees
21 Apr - 22 Apr
Centrally located in Panama City, Hotel Riu Plaza Panama is within a 15-minute walk of Crown Casino and Fiesta Casino.
Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is AU$420 per night from 21 Apr to 22 Apr
AU$420
includes taxes & fees
21 Apr - 22 Apr
When you stay at Dreams Playa Bonita Panama - All Inclusive in Veracruz, you'll be on the beach, within a 15-minute drive of Albrook Shopping Mall and Cinta ...
Dreams Playa Bonita Panama - All Inclusive
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Fully refundable
The price is AU$215 per night from 25 Apr to 26 Apr
AU$215
includes taxes & fees
25 Apr - 26 Apr
Located in Tocumen, Crowne Plaza Panama Airport by IHG is within a 10-minute drive of Los Pueblos Commercial Center and Metromall Panama.
Crowne Plaza Panama Airport by IHG
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Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AU$164 per night from 30 Mar to 31 Mar
AU$164
includes taxes & fees
30 Mar - 31 Mar
With a stay at Decapolis Hotel Panama City, you'll be centrally located in Panama City, steps from Avenida Balboa and Multicentro Panama.
Decapolis Hotel Panama City
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.