Book Holiday Homes in Los Santos

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in Los Santos

Beach House / 6 People / Pool / Pet Friendly / Tourist Area

Beach House / 6 People / Pool / Pet Friendly / Tourist Area

Río Hato
With a stay at this vacation home, you'll be centrally located in Rio Hato, a 3-minute drive from Playa Blanca and 7 minutes from Parroquia Santiago Apóstol ...
Beach House / 6 People / Pool / Pet Friendly / Tourist Area
Panama Santa Clara Beach Residence

Panama Santa Clara Beach Residence

Cocle
With a stay at this vacation home in Rio Hato, you'll be by the sea, within a 15-minute drive of Playa Blanca and Santa Clara Beach.
Panama Santa Clara Beach Residence
Beautiful Beach House in Las Tablas Panama

Beautiful Beach House in Las Tablas Panama

Las Tablas
With a stay at this vacation home in Las Tablas, you'll be by the sea, just a 1-minute walk from Peninsula de Azuero and 11 minutes by foot from El Uverito ...
Beautiful Beach House in Las Tablas Panama
Save an average of 15% on thousands of hotels when you're signed in
Santa Clara ocean front beach house… from your lawn right onto the sand.

Santa Clara ocean front beach house… from your lawn right onto the sand.

Santa Clara
With a stay at this vacation home in Rio Hato, you'll be within a 15-minute drive of Playa Blanca and Santa Clara Beach.
Santa Clara ocean front beach house… from your lawn right onto the sand.
Villa Nomada

Villa Nomada

3.5 out of 5
Via Doctor Belisario Porras, Playa Venao, Las Escobas del Venado, Los Santos
The price is AU$818 per night from 24 Nov to 25 Nov
AU$818
includes taxes & fees
24 Nov - 25 Nov
When you stay at this vacation home in Las Escobas del Venado, you'll be on the beach, within a 10-minute walk of Venao Beach and Peninsula de Azuero.
Villa Nomada
Luxury Villa in Buenaventura

Luxury Villa in Buenaventura

El Chirú
With a stay at this vacation home in El Chiru, you'll be within a 10-minute drive of Playa Blanca and Buenaventura Marina.
Luxury Villa in Buenaventura
Susan Fish Camp in Playa Morrillo, Veraguas

Susan Fish Camp in Playa Morrillo, Veraguas

Morrillo
Located in Torio, this vacation home is by the sea, within a 15-minute drive of Peninsula de Azuero and Morrillo Beach.
Susan Fish Camp in Playa Morrillo, Veraguas
Arrue's Coastal Escape

Arrue's Coastal Escape

Pedasi
With a stay at this vacation home in Pedasí, you'll be on the beach, just steps from Peninsula de Azuero and a 5-minute drive from Playa El Toro.
Arrue's Coastal Escape
Luxury 4BR Villa + Guesthouse & Pool @Buenaventura

Luxury 4BR Villa + Guesthouse & Pool @Buenaventura

El Chirú
With a stay at this vacation home in El Chiru, you'll be within a 10-minute drive of Playa Blanca and Buenaventura Marina.
Luxury 4BR Villa + Guesthouse & Pool @Buenaventura
Don't see what you're looking for?
See all available properties in Los Santos
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Los Santos Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Los Santos vacation homes are the perfect way for you to wing it.

Holiday houses in Los Santos let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Los Santos in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Los Santos adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Los Santos with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Los Santos vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Los Santos Holiday Homes essential information

Accommodation
54 Holiday Homes
Lowest Price
AU$135
Highest Price
AU$818
Popular accommodation
Beach House / 6 People / Pool / Pet Friendly / Tourist Area, Panama Santa Clara Beach Residence, Beautiful Beach House in Las Tablas Panama, Santa Clara ocean front beach house… from your lawn right onto the sand., Villa Nomada, Luxury Villa in Buenaventura, Susan Fish Camp in Playa Morrillo, Veraguas, Arrue's Coastal Escape , Luxury 4BR Villa + Guesthouse & Pool @Buenaventura

Top trending hotels in Los Santos

Villa Marina Lodge & Condos

Villa Marina Lodge & Condos

3.5 out of 5
Playa Venao, Las Escobas del Venado, Los Santos
Fully refundableReserve now, pay when you stay
The price is AU$264 per night from 24 Nov to 25 Nov
AU$264
includes taxes & fees
24 Nov - 25 Nov
With a stay at Villa Marina Lodge & Condos in Las Escobas del Venado, you'll be on the beach, within a 10-minute drive of Venao Beach and Peninsula de ...
Villa Marina Lodge & Condos
Casa Lajagua

Casa Lajagua

3 out of 5
Calle principal de Pedasi, Pedasí, Panama
The price is AU$144 per night from 23 Nov to 24 Nov
AU$144
includes taxes & fees
23 Nov - 24 Nov
Located in Pedasí, Casa Lajagua is a 1-minute drive from Peninsula de Azuero and 6 minutes from Playa El Arenal.
Casa Lajagua
Hotel Punta Franca

Hotel Punta Franca

3 out of 5
Camino a Puerto Escondido, Los Destiladeros, Punta Mala, Los Santos
The price is AU$160 per night from 26 Nov to 27 Nov
AU$160
includes taxes & fees
26 Nov - 27 Nov
With a stay at Hotel Punta Franca in Punta Mala, you'll be on the beach, just a 1-minute walk from Peninsula de Azuero and 9 minutes by foot from Los Destiladeros ...
Hotel Punta Franca
Save an average of 15% on thousands of hotels when you're signed in
Hotel Presidente

Hotel Presidente

3.5 out of 5
Calle Moises Espino, y Calle Pablo Arosemena, Las Tablas
The price is AU$135 per night from 23 Nov to 24 Nov
AU$135
includes taxes & fees
23 Nov - 24 Nov
With a stay at Hotel Presidente in Las Tablas, you'll be just steps from Peninsula de Azuero and Belisario Porras Park.
Hotel Presidente
Don't see what you're looking for?
See all available properties in Los Santos
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More ways to explore Los Santos