Book Holiday Homes in Mayo

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Featured Holiday Homes in Mayo

Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock

Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock

Branford
When you a stay at this vacation home in Branford, you'll be on the waterfront, just steps from Santa Fe River and Fort White Wildlife and Environmental ...
Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock
Steinhatchee Home w/ Boat Parking: 1 Mi to Marina

Steinhatchee Home w/ Boat Parking: 1 Mi to Marina

Steinhatchee
Located in Steinhatchee, this vacation home is by the sea, within a 5-minute drive of Sea Hag Marina and Steinhatchee Public Boat Ramp.
Steinhatchee Home w/ Boat Parking: 1 Mi to Marina
Scallop and Fishing Paradise

Scallop and Fishing Paradise

Steinhatchee
The price is AU$522 per night from 14 Apr to 15 Apr
AU$522
includes taxes & fees
14 Apr - 15 Apr
Located in Steinhatchee, this vacation home is within a 15-minute walk of Steinhatchee Public Boat Ramp and Sea Hag Marina.
Scallop and Fishing Paradise
Save an average of 15% on thousands of hotels when you're signed in
3-bedroom Riverfront home with private boat dock and view of Steinhatchee River.

3-bedroom Riverfront home with private boat dock and view of Steinhatchee River.

Steinhatchee
When you stay at this vacation home in Steinhatchee, you'll be on the waterfront, within a 5-minute drive of Fort Steinhatchee Pier and Sea Hag Marina.
3-bedroom Riverfront home with private boat dock and view of Steinhatchee River.
Dekle Beach Darling - Beautiful Sunsets and Great Fishing

Dekle Beach Darling - Beautiful Sunsets and Great Fishing

Perry
Located in Perry, this vacation home is a 5-minute drive from Spring Warrior Creek Conservation Area and 8 minutes from Keaton Beach Coastal Park.
Dekle Beach Darling - Beautiful Sunsets and Great Fishing
The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee

The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee

Branford
Located in Branford, this vacation home is on the waterfront, within a 15-minute drive of Ichetucknee River and William Guy Lemmon Memorial Park.
The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

Fort White,
When you a stay at this vacation home in Fort White, you'll be on a river, just steps from Ichetucknee Springs State Park and Ichetucknee River.
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River
Secluded and very unique OFF grid country home, 15 springs within an hour.

Secluded and very unique OFF grid country home, 15 springs within an hour.

MAYO
When you stay at this vacation home in Mayo, you'll be on the waterfront, within a 5-minute drive of Suwannee River and Lafayette Blue Springs State Park.
Secluded and very unique OFF grid country home, 15 springs within an hour.
Pet-Friendly Florida Escape w/ Patio & Fire Pit!

Pet-Friendly Florida Escape w/ Patio & Fire Pit!

O'Brien
Located in O Brien, this vacation home is a 4-minute drive from Ichetucknee Springs State Park and 7 minutes from Santa Fe River.
Pet-Friendly Florida Escape w/ Patio & Fire Pit!
Don't see what you're looking for?
See all available properties in Mayo
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mayo Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Mayo vacation homes are the perfect way for you to wing it.

Holiday houses in Mayo let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Mayo in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Mayo adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Mayo with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Mayo vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Mayo Holiday Homes essential information

Accommodation
186 Holiday Homes
Lowest Price
AU$159
Highest Price
AU$522
Popular accommodation
Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock, Steinhatchee Home w/ Boat Parking: 1 Mi to Marina, Scallop and Fishing Paradise, 3-bedroom Riverfront home with private boat dock and view of Steinhatchee River., Dekle Beach Darling - Beautiful Sunsets and Great Fishing , The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee, ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River, Secluded and very unique OFF grid country home, 15 springs within an hour., Pet-Friendly Florida Escape w/ Patio & Fire Pit!

Top trending hotels in Mayo

Suwannee River Rendezvous

Suwannee River Rendezvous

2.5 out of 5
828 NE Primrose Rd, Mayo, FL
Fully refundableReserve now, pay when you stay
The price is AU$159 per night from 19 Apr to 20 Apr
AU$159
includes taxes & fees
19 Apr - 20 Apr
Located in Mayo, Suwannee River Rendezvous is within a 15-minute drive of Suwannee River and Lafayette County Library.
Suwannee River Rendezvous
Cindys Motel

Cindys Motel

2.5 out of 5
487 W Main St, Mayo, FL
Fully refundableReserve now, pay when you stay
The price is AU$179 per night from 11 Apr to 12 Apr
AU$179
includes taxes & fees
11 Apr - 12 Apr
With a stay at Cindys Motel in Mayo, you'll be a 3-minute walk from Veteran's Memorial Park of Mayo and 8 minutes by foot from Lafayette County Library.
Cindys Motel
Secluded and very unique OFF grid country home, 15 springs within an hour.

Secluded and very unique OFF grid country home, 15 springs within an hour.

MAYO
When you stay at this vacation home in Mayo, you'll be on the waterfront, within a 5-minute drive of Suwannee River and Lafayette Blue Springs State Park.
Secluded and very unique OFF grid country home, 15 springs within an hour.
Save an average of 15% on thousands of hotels when you're signed in
Best Western Plus Madison

Best Western Plus Madison

2.5 out of 5
167 SE Bandit Street, Madison, FL
Fully refundableReserve now, pay when you stay
The price is AU$241 per night from 29 Apr to 30 Apr
AU$241
includes taxes & fees
29 Apr - 30 Apr
Located in Madison, Best Western Plus Madison is in a rural location, a 4-minute drive from Yogi Bear's Jellystone Park and 8 minutes from Lake Frances Recreation ...
Best Western Plus Madison
Don't see what you're looking for?
See all available properties in Mayo
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.