Book Holiday Homes in Mayo

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Featured Holiday Homes in Mayo

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

Live Oak
The price is AU$427 per night from 5 Dec to 6 Dec
AU$427
includes taxes & fees
5 Dec - 6 Dec
Located in Live Oak, this vacation home is on the waterfront, within a 10-minute drive of Shands Live Oak Regional Medical Center and Suwannee County Historical ...
Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
Scallop and Fishing Paradise

Scallop and Fishing Paradise

Steinhatchee
The price is AU$475 per night from 24 Nov to 25 Nov
AU$475
includes taxes & fees
24 Nov - 25 Nov
Located in Steinhatchee, this vacation home is within a 15-minute walk of Steinhatchee Public Boat Ramp and Sea Hag Marina.
Scallop and Fishing Paradise
Canal front house with private dock and fish house, just 15 minutes to the Gulf

Canal front house with private dock and fish house, just 15 minutes to the Gulf

Steinhatchee
Located in Steinhatchee, this vacation home is on the waterfront, within a 5-minute drive of Fort Steinhatchee Pier and Sea Hag Marina.
Canal front house with private dock and fish house, just 15 minutes to the Gulf
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The River House

The River House

Mayo
Located in Mayo, this vacation home is on the waterfront, within a 15-minute drive of Suwannee River and Lafayette County Library.
The River House
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River

Fort White,
When you a stay at this vacation home in Fort White, you'll be on a river, just steps from Ichetucknee Springs State Park and Ichetucknee River.
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River
Newer Riverfront Home Overlooking the River

Newer Riverfront Home Overlooking the River

Steinhatchee
Located in Steinhatchee, this vacation home is on the waterfront, within a 5-minute drive of Fort Steinhatchee Pier and Sea Hag Marina.
Newer Riverfront Home Overlooking the River
Peaceful McAlpin Home on 5 Acres w/ Private Deck!

Peaceful McAlpin Home on 5 Acres w/ Private Deck!

McAlpin
With a stay at this vacation home in Live Oak, you'll be within a 15-minute drive of Suwannee County Historical Museum and First Federal Sportsplex.
Peaceful McAlpin Home on 5 Acres w/ Private Deck!
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

obrien
When you stay at this vacation home in O Brien, you'll be on the beach and steps from Suwannee River.
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
Custom Built Home steps from the Santa Fe River

Custom Built Home steps from the Santa Fe River

Branford
With a stay at this vacation home in Branford, you'll be on the waterfront, just a 1-minute walk from Santa Fe River and 11 minutes by foot from Fort White Wildlife ...
Custom Built Home steps from the Santa Fe River
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mayo Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Mayo vacation homes are the perfect way for you to wing it.

Holiday houses in Mayo let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Mayo in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Mayo adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Mayo with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Mayo vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Mayo Holiday Homes essential information

Accommodation
157 Holiday Homes
Lowest Price
AU$160
Highest Price
AU$475
Popular accommodation
Beautiful 2 story house overlooking the water. Has arcade & Close to the springs, Scallop and Fishing Paradise, Canal front house with private dock and fish house, just 15 minutes to the Gulf, The River House, ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River, Newer Riverfront Home Overlooking the River, Peaceful McAlpin Home on 5 Acres w/ Private Deck!, Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!, Custom Built Home steps from the Santa Fe River

Top trending hotels in Mayo

Cindys Motel

Cindys Motel

2.5 out of 5
487 W Main St, Mayo, FL
Fully refundableReserve now, pay when you stay
The price is AU$160 per night from 27 Nov to 28 Nov
AU$160
includes taxes & fees
27 Nov - 28 Nov
With a stay at Cindys Motel in Mayo, you'll be a 3-minute walk from Veteran's Memorial Park of Mayo and 8 minutes by foot from Lafayette County Library.
Cindys Motel
The River House

The River House

Mayo
Located in Mayo, this vacation home is on the waterfront, within a 15-minute drive of Suwannee River and Lafayette County Library.
The River House
The Best memories are made on the Suwannee River

The Best memories are made on the Suwannee River

Mayo
The price is AU$460 per night from 1 Dec to 2 Dec
AU$460
includes taxes & fees
1 Dec - 2 Dec
When you a stay at this vacation home in Mayo, you'll be on the waterfront, just steps from Suwannee River and Lafayette Blue Springs State Park.
The Best memories are made on the Suwannee River
Save an average of 15% on thousands of hotels when you're signed in
Best Western Plus Madison

Best Western Plus Madison

2.5 out of 5
167 SE Bandit Street, Madison, FL
Fully refundableReserve now, pay when you stay
The price is AU$222 per night from 4 Dec to 5 Dec
AU$222
includes taxes & fees
4 Dec - 5 Dec
Located in Madison, Best Western Plus Madison is in a rural location, a 4-minute drive from Yogi Bear's Jellystone Park and 8 minutes from Lake Frances Recreation ...
Best Western Plus Madison
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.