Good hotel in a good location, only about 20 minutes away from the tourist locations. The only thing to let the hotel down is that the cleaners didn't tend to the room during the 4 days we were there, so no fresh towels and had to ask at reception for some toilet roll. Most of the staff were lovely and friendly, apart from one man working the Friday evening who made us feel like he was doing us a favour by letting us stay there and it therefore tainted our experience a little bit. Rooms were quiet, but think we were the only ones staying at the time as it's a very small hotel on one floor with only about 5 rooms for customers. Would probably consider this hotel again if we were to come back to rome, just because of how cheap it was and the location.
Would recommend doing the hop on hop off bus so you can get to see all the tourist locations in one day, or buy a multi day ticket and split it over a couple of days.
At Vatican city there will be lots of people trying to sell skip the queue tickets, DON'T BUY THEM, you don't need to pay to get in there and the queue only takes around 15 minutes, they will all tell you that it costs around 26 euros to get in but they will give you tickets for 30 euros so you don't have to queue, it's just a tourist scam!