Book Santiago hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Santiago

4 Apr - 5 Apr
Tonight
Check prices in Santiago for tonight, 4 Apr - 5 Apr
5 Apr - 6 Apr
Tomorrow night
Check prices in Santiago for tomorrow night, 5 Apr - 6 Apr

Cheap Santiago hotels

Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
The price is AU$170 per night from 11 Apr to 12 Apr
AU$170
includes taxes & fees
11 Apr - 12 Apr
Located in Santiago, Hotel Gran David is in a rural location, within a 15-minute walk of Plaza Banconal and Omar Torrijos Herrera Stadium.
Hotel Gran David
HOTEL PLAZA COROTÚ

HOTEL PLAZA COROTÚ

2 out of 5
Carr. Panamericana, Santiago, Provincia de Veraguas
Fully refundableReserve now, pay when you stay
The price is AU$78 per night from 7 Apr to 8 Apr
AU$78
includes taxes & fees
7 Apr - 8 Apr
With a stay at HOTEL PLAZA COROTÚ in Santiago, you'll be within a 5-minute drive of Plaza Banconal and Parque Nacional Cerro Hoya.
HOTEL PLAZA COROTÚ
Hostal Travelers

Hostal Travelers

2 out of 5
Santiago de Veraguas, Paso las Tablas, Santiago, Veraguas
Located in Santiago, Hostal Travelers is within a 15-minute walk of Omar Torrijos Herrera Stadium and Escuela Normal Juan Demostenes Arosemena.
Get rates
Hostal Travelers
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone

Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone

2 out of 5
Santiago
With a stay at this vacation home in Santiago, you'll be within a 5-minute drive of Plaza Banconal and Parque Nacional Cerro Hoya.
Get rates
Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
The price is AU$148 per night from 11 Apr to 12 Apr
AU$148
includes taxes & fees
11 Apr - 12 Apr
A stay at Hotel Mykonos Panama places you in the heart of Nuevo Santiago, within a 5-minute drive of Plaza Banconal and Parque Nacional Cerro Hoya.
Hotel Mykonos Panama
HOTEL VISTA LAGO

HOTEL VISTA LAGO

3 out of 5
Rincón Largo, La Pena, Santiago de Veraguas
Fully refundableReserve now, pay when you stay
The price is AU$133 per night from 30 Apr to 1 May
AU$133
includes taxes & fees
30 Apr - 1 May
Located in La Pena, HOTEL VISTA LAGO is within a 15-minute drive of Parque Acuatico Italia Guadalupe Panama and Plaza Banconal.
HOTEL VISTA LAGO
Hotel Galería

Hotel Galería

3 out of 5
Vía Interamericana Santiago, Km 232.88, Nuevo Santiago
Fully refundable
The price is AU$124 per night from 7 Apr to 8 Apr
AU$124
includes taxes & fees
7 Apr - 8 Apr
With a stay at Hotel Galería in Nuevo Santiago, you'll be within a 5-minute drive of Plaza Banconal and Parque Nacional Cerro Hoya.
Hotel Galería
Cabañas Palma Real

Cabañas Palma Real

3 out of 5
Las Colomas, Santiago Sur via principal, 68035902, Santiago Sur, Provincia de Veraguas
The price is AU$119 per night from 18 Apr to 19 Apr
AU$119
includes taxes & fees
18 Apr - 19 Apr
With a stay at Cabañas Palma Real in Santiago Sur, you'll be 14.6 mi (23.5 km) from Mariato Beach and 22 mi (35.5 km) from Torio Beach.
Cabañas Palma Real
Hotel La Hacienda

Hotel La Hacienda

3 out of 5
Via Interamericana, Rodrigo Luque, Veraguas
With a stay at Hotel La Hacienda in Rodrigo Luque, you'll be steps from Parque Acuatico Italia Guadalupe Panama and a 1-minute drive from Plaza Banconal.
Get rates
Hotel La Hacienda
Don't see what you're looking for?
See all available properties in Santiago
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santiago

Stress tip: Stand up, walk around, book a Panama hotel, go to the airport, jump on a plane, never return. Or something like that. While you'll have difficulty staying in the very centre, there is accommodation nearby. Choose from 2 options within 10 kilometres of Santiago's heart.

Book yourself a room at Hotel Mykonos Panama and Hotel Vista Lago Ecoresort and know that a hot shower and comfy bed are just a short drive away.

La Arena is another place where you can kick back and acquaint yourself with the room service menu. Located 55 kilometres east of Santiago, it's where you'll discover the Church of St. Athanasius and the Museo de la Nacionalidad. If you want to stay in La Arena, consider the Los Guayacanes and Gran Hotel Azuero. 100 kilometres to the east of Santiago you'll find Rio Hato, which is home to the Sheraton Bijao Beach Resort - All Inclusive and Villa Botero By Casa Mojito Bed and Breakfast. If you're staying in Rio Hato, set aside some time to check out Farallon Island and Parroquia Santiago Apóstol de Río Hato.

So when it's time to head to Santiago, lastminute.com.au's the one to get you there. Like we've said, travel is in our DNA! (don't fact check this).

Santiago hotels essential information

Accommodation
12 hotels
Lowest Price
AU$78
Highest Price
AU$170
Popular hotels
Hotel Gran David, HOTEL PLAZA COROTÚ, Hostal Travelers, Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone, Hotel Mykonos Panama, HOTEL VISTA LAGO, Hotel Galería, Cabañas Palma Real, Hotel La Hacienda

Most recent Santiago hotel reviews

Hotel Mykonos Panama
lastminute.com.au Verified Review
5 / 5
We stayed for a religious gathering and it couldn’t have been more convenient. Breakfast is good. Dining options were great and affordable. Close to the Santiago Mall.
A verified traveller stayed at Hotel Mykonos Panama
Posted 1 day ago
Hotel Mykonos Panama

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.