Southeast Missouri Holiday Deals
Top hotels for your Southeast Missouri holiday
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$176 per night from 13 Apr to 14 Apr
AU$176
includes taxes & fees
13 Apr - 14 Apr
When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive ...
Great roadtrip hotel
"It was a great hotel and the staff were very helpful to us with our kids at breakfast time. The kids loved getting popcorn from the staff after a long day of driving."
Reviewed on 4 Apr. 2025
The Riverview
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$180 per night from 21 Apr to 22 Apr
AU$180
includes taxes & fees
21 Apr - 22 Apr
When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Shawnee National Forest and Mississippi ...
"Love the proximity to SEMO campus"
Reviewed on 6 Apr. 2025
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St, Farmington, MO
Fully refundableReserve now, pay when you stay
The price is AU$101 per night from 13 Apr to 14 Apr
AU$101
includes taxes & fees
13 Apr - 14 Apr
Located in Farmington, Baymont Inn and Suites by Wyndham Farmington, MO is in the historical district, within a 15-minute drive of Crown Pointe Golf Club and ...
"Great stay."
Reviewed on 1 Apr. 2025
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Elephant Rocks State Park
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
Echo Bluff State Park
You can take time to visit Echo Bluff State Park during your travels to Salem. While you're in the area, stroll along the riverfront.
Lake Wappapello
Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.
Recommended cities for you
- Anaheim Holidays
- Atlanta Holidays
- Atlantic City Holidays
- Austin Holidays
- Boston Holidays
- Charleston Holidays
- Charlotte Holidays
- Chicago Holidays
- Dallas Holidays
- Daytona Beach Holidays
- Denver Holidays
- Fort Lauderdale Holidays
- Fort Myers Holidays
- Grand Canyon Holidays
- Honolulu Holidays
- Houston Holidays
- Key West Holidays
- Las Vegas Holidays
- Los Angeles Holidays
- Miami Holidays
- Monterey Holidays
- Montreal Holidays
- Myrtle Beach Holidays
- Naples Holidays
- Nashville Holidays
- New Orleans Holidays
- New York Holidays
- Niagara Falls Holidays
- Ocean City Holidays
- Orlando Holidays
- Palm Springs Holidays
- Philadelphia Holidays
- Phoenix Holidays
- Portland Holidays
- Reno Holidays
- San Antonio Holidays
- San Diego Holidays
- San Francisco Holidays
- Sarasota Holidays
- Savannah Holidays
- Seattle Holidays
- Sedona Holidays
- St. Petersburg - Clearwater Holidays
- Tahoe City Holidays
- Tampa Holidays
- Toronto Holidays
- Vancouver Holidays
- Washington Holidays
Book your Southeast Missouri holiday package
Top picks
Hotels
Maui All Inclusive HotelsSt. Lawrence Seaway Pet Friendly HotelsAccommodation in Central CoastOahu All Inclusive HotelsAccommodation in Hawaii IslandAccommodation in KauaiHawaii Island Apartment HotelsAccommodation in North ShoreHawaii Island Luxury HotelsAccommodation in MauiAccommodation in Vail - Beaver Creek Ski AreaOahu Family HotelsMaui Family HotelsAccommodation in OahuAccommodation in Napa ValleyKauai Family HotelsAccommodation in Anna Maria IslandKauai Apartment Hotels
^Savings based on all package bookings made with Flight + Hotel on lastminute.com.au from January 1, 2019 to December 31, 2019, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.