Book Southeast Missouri hotels
More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)
We keep it easy with the option to pay now or later on select accommodation
Book up 'til the last second - millions of rooms to crash tonight^
Check hotel availability in Southeast Missouri
Cheap Southeast Missouri hotels
The Riverview
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$170 per night from 4 May to 5 May
AU$170
includes taxes & fees
4 May - 5 May
When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Shawnee National Forest and Mississippi ...
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$175 per night from 27 Apr to 28 Apr
AU$175
includes taxes & fees
27 Apr - 28 Apr
When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive ...
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St, Farmington, MO
Fully refundableReserve now, pay when you stay
The price is AU$95 per night from 27 Apr to 28 Apr
AU$95
includes taxes & fees
27 Apr - 28 Apr
Located in Farmington, Baymont Inn and Suites by Wyndham Farmington, MO is in the historical district, within a 15-minute drive of Crown Pointe Golf Club and ...
Save an average of 15% on thousands of hotels when you're signed in
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
The price is AU$131 per night from 23 Apr to 24 Apr
AU$131
includes taxes & fees
23 Apr - 24 Apr
Located in Poplar Bluff, Motel 6 Poplar Bluff, MO is a 3-minute drive from Poplar Bluff Regional Medical Center and 5 minutes from Mark Twain National ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Fully refundable
The price is AU$182 per night from 4 May to 5 May
AU$182
includes taxes & fees
4 May - 5 May
When you stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG in Cape Girardeau, you'll be near the airport, within a 10-minute drive of Shawnee ...
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Fully refundableReserve now, pay when you stay
The price is AU$139 per night from 20 Apr to 21 Apr
AU$139
includes taxes & fees
20 Apr - 21 Apr
When you stay at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau in Jackson, you'll be in the business district, within a 15-minute drive of Shawnee ...
Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is AU$154 per night from 21 Apr to 22 Apr
AU$154
includes taxes & fees
21 Apr - 22 Apr
A stay at Pear Tree Inn Sikeston places you in the heart of Sikeston, within a 5-minute walk of The Book Bug and City of Miner Convention Center.
The Farmstead Hotel
778 E 3rd St, Caruthersville, MO
Fully refundableReserve now, pay when you stay
The price is AU$148 per night from 27 Apr to 28 Apr
AU$148
includes taxes & fees
27 Apr - 28 Apr
Located in Caruthersville, The Farmstead Hotel is a 4-minute walk from Century Casino Caruthersville and 5 minutes by foot from Mississippi River.
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$104 per night from 22 Apr to 23 Apr
AU$104
includes taxes & fees
22 Apr - 23 Apr
With a stay at Pear Tree Inn Cape Girardeau Near the Medical Center, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National ...
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
**Terms and Conditions apply.
^Subject to availability and chosen travel dates.
Southeast Missouri hotels essential information
Accommodation | 563 hotels |
|---|---|
Lowest Price | AU$95 |
Highest Price | AU$182 |
Popular hotels | The Riverview, Drury Plaza Hotel Cape Girardeau Conference Center, Baymont Inn and Suites by Wyndham Farmington, MO, Motel 6 Poplar Bluff, MO, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Pear Tree Inn Sikeston, The Farmstead Hotel, Pear Tree Inn Cape Girardeau Near the Medical Center |
Most recent Southeast Missouri hotel reviews
lastminute.com.au Verified Review
5 / 5
First time at a Drury. Very nice.
A verified traveller stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Posted 2 days ago
Other cities near Southeast Missouri
- Chesterfield Hotels
- Cape Girardeau Hotels
- Carbondale Hotels
- Sikeston Hotels
- Poplar Bluff Hotels
- Farmington Hotels
- Fenton Hotels
- Eminence Hotels
- East St. Louis Hotels
- Arnold Hotels
- Ste Genevieve Hotels
- Kirkwood Hotels
- Ozarks Hotels
- Richmond Heights Hotels
- West Plains Hotels
- Brentwood Hotels
- Eureka Hotels
- Southern Illinois Hotels
- Dyersburg Hotels
- Jackson Hotels
Hotels near airport
Other top Southeast Missouri hotels
- Baymont Inn and Suites by Wyndham Farmington, MO
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Pear Tree Inn Sikeston
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Pear Tree Inn Cape Girardeau West
- Drury Inn & Suites Sikeston, MO
- Comfort Inn Festus - St Louis South
More ways to explore Southeast Missouri
Top picks
Hotels
Maui All Inclusive HotelsSt. Lawrence Seaway Pet Friendly HotelsAccommodation in Central CoastAccommodation in Aspen SnowmassOahu All Inclusive HotelsAccommodation in Hawaii IslandAccommodation in KauaiHawaii Island Apartment HotelsAccommodation in North ShoreHawaii Island Luxury HotelsAccommodation in MauiAccommodation in Vail - Beaver Creek Ski AreaOahu Family HotelsMaui Family HotelsAccommodation in OahuAccommodation in Napa ValleyAccommodation in Anna Maria IslandKauai Family HotelsKauai Apartment Hotels
**Terms and Conditions apply.
^Subject to availability and chosen travel dates.