Book Southern Illinois hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Southern Illinois

9 Mar - 10 Mar
Tonight
Check prices in Southern Illinois for tonight, 9 Mar - 10 Mar
10 Mar - 11 Mar
Tomorrow night
Check prices in Southern Illinois for tomorrow night, 10 Mar - 11 Mar

Cheap Southern Illinois hotels

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is AU$201 per night from 7 Apr to 8 Apr
AU$201
includes taxes & fees
7 Apr - 8 Apr
A stay at Drury Plaza Hotel Mt. Vernon places you in the heart of Mount Vernon, within a 5-minute drive of King City Square Shopping Center and Crossroads Community ...
Drury Plaza Hotel Mt. Vernon
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
The price is AU$95 per night from 16 Mar to 17 Mar
AU$95
includes taxes & fees
16 Mar - 17 Mar
Located in O'Fallon, Super 8 by Wyndham O'Fallon is within a 10-minute drive of Shiloh Dog Park and Scott Air Force Base.
Super 8 by Wyndham O'Fallon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive, O'Fallon, IL
Fully refundableReserve now, pay when you stay
The price is AU$207 per night from 16 Mar to 17 Mar
AU$207
includes taxes & fees
16 Mar - 17 Mar
A stay at Drury Inn & Suites St. Louis O'Fallon, IL places you in the heart of O'Fallon, within a 5-minute drive of HSHS St. Elizabeth's Hospital and Clayton ...
Drury Inn & Suites St. Louis O'Fallon, IL
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

2.5 out of 5
1240 E Chain Of Rocks Rd, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is AU$106 per night from 10 Mar to 11 Mar
AU$106
includes taxes & fees
10 Mar - 11 Mar
With a stay at Red Lion Inn & Suites Pontoon Beach in Granite City, you'll be within a 10-minute drive of Horseshoe Lake State Park and Lewis and Clark Interpretive ...
Red Lion Inn & Suites Pontoon Beach
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
The price is AU$183 per night from 30 Mar to 31 Mar
AU$183
includes taxes & fees
30 Mar - 31 Mar
Located in Fairview Heights, Drury Inn & Suites St. Louis Fairview Heights is within a 15-minute drive of Mississippi River and America's Center Convention ...
Drury Inn & Suites St. Louis Fairview Heights
Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 out of 5
777 Walkers Bluff Way, Carterville, IL
Fully refundableReserve now, pay when you stay
The price is AU$229 per night from 10 Mar to 11 Mar
AU$229
includes taxes & fees
10 Mar - 11 Mar
With a stay at Walker's Bluff Casino Resort in Carterville, you'll be 8 mi (12.8 km) from Southern Illinois University and 11.4 mi (18.4 km) from Shawnee National ...
Walker's Bluff Casino Resort
Red Lion Inn & Suites Caseyville

Red Lion Inn & Suites Caseyville

2 out of 5
8950 Tucker Dr, Caseyville, IL
Fully refundableReserve now, pay when you stay
The price is AU$96 per night from 11 Mar to 12 Mar
AU$96
includes taxes & fees
11 Mar - 12 Mar
Located in Caseyville, Red Lion Inn & Suites Caseyville is within a 15-minute drive of Busch Stadium and City Museum.
Red Lion Inn & Suites Caseyville
Baymont by Wyndham Marion

Baymont by Wyndham Marion

2.5 out of 5
2608 W Main St, Marion, IL
Fully refundableReserve now, pay when you stay
The price is AU$163 per night from 16 Mar to 17 Mar
AU$163
includes taxes & fees
16 Mar - 17 Mar
With a stay at Baymont by Wyndham Marion in Marion, you'll be within a 5-minute drive of The Bark Park and Williamson County Historical Museum.
Baymont by Wyndham Marion
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St, Marion, IL
Fully refundableReserve now, pay when you stay
The price is AU$206 per night from 7 Apr to 8 Apr
AU$206
includes taxes & fees
7 Apr - 8 Apr
A stay at Drury Inn & Suites Marion places you in the heart of Marion, within a 5-minute drive of Kokopelli Golf Club and Marion Stadium.
Drury Inn & Suites Marion
Don't see what you're looking for?
See all available properties in Southern Illinois
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.

Southern Illinois hotels essential information

Accommodation
961 hotels
Lowest Price
AU$95
Highest Price
AU$229
Popular hotels
Drury Plaza Hotel Mt. Vernon, Super 8 by Wyndham O'Fallon, Drury Inn & Suites St. Louis O'Fallon, IL, Red Lion Inn & Suites Pontoon Beach, Drury Inn & Suites St. Louis Fairview Heights, Walker's Bluff Casino Resort, Red Lion Inn & Suites Caseyville, Baymont by Wyndham Marion, Drury Inn & Suites Marion

Most recent Southern Illinois hotel reviews

Drury Inn & Suites St. Louis O'Fallon, IL
lastminute.com.au Verified Review
5 / 5
This was the first hotel stay for my family that we have enjoyed. It was super quiet even though the hotel was bustling with people, there were plenty of options in the area for food (including inside the hotel), and housekeeping was superb when we need a change of sheets. I definitely recommend and will stay in the future if we are in the area.
A verified traveller stayed at Drury Inn & Suites St. Louis O'Fallon, IL
Posted 13 hours ago
Drury Inn & Suites St. Louis O'Fallon, IL

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.