Book East Prairie hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in East Prairie

4 Apr - 5 Apr
Tonight
Check prices in East Prairie for tonight, 4 Apr - 5 Apr
5 Apr - 6 Apr
Tomorrow night
Check prices in East Prairie for tomorrow night, 5 Apr - 6 Apr

Cheap East Prairie hotels

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is AU$155 per night from 9 Apr to 10 Apr
AU$155
includes taxes & fees
9 Apr - 10 Apr
A stay at Pear Tree Inn Sikeston places you in the heart of Sikeston, within a 5-minute walk of The Book Bug and City of Miner Convention Center.
Pear Tree Inn Sikeston
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is AU$155 per night from 1 May to 2 May
AU$155
includes taxes & fees
1 May - 2 May
Located in Sikeston, Best Western Plus Sikeston is within a 15-minute walk of City of Miner Convention Center and The Book Bug.
Best Western Plus Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is AU$180 per night from 4 May to 5 May
AU$180
includes taxes & fees
4 May - 5 May
A stay at Drury Inn & Suites Sikeston, MO places you in the heart of Sikeston, steps from City of Miner Convention Center and 6 minutes by foot from The Book ...
Drury Inn & Suites Sikeston, MO
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

2.5 out of 5
810 BREAM BOULEVARD, Union City, TN
Fully refundable
The price is AU$201 per night from 20 Apr to 21 Apr
AU$201
includes taxes & fees
20 Apr - 21 Apr
A stay at Holiday Inn Express & Suites Union City by IHG places you in the heart of Union City, a 3-minute drive from Discovery Park of America and 5 minutes ...
Holiday Inn Express & Suites Union City by IHG
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61, Portageville, MO
Fully refundableReserve now, pay when you stay
The price is AU$96 per night from 13 Apr to 14 Apr
AU$96
includes taxes & fees
13 Apr - 14 Apr
When you stay at New Orleans Inn Portageville in Portageville, you'll be 11 minutes by car from Marston Community Center.
New Orleans Inn Portageville
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is AU$138 per night from 15 Apr to 16 Apr
AU$138
includes taxes & fees
15 Apr - 16 Apr
With a stay at Days Inn and Suites by Wyndham Sikeston in Sikeston, you'll be within a 5-minute drive of The Book Bug and City of Miner Convention Center.
Days Inn and Suites by Wyndham Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive, Sikeston, MO
Fully refundableReserve now, pay when you stay
The price is AU$196 per night from 13 Apr to 14 Apr
AU$196
includes taxes & fees
13 Apr - 14 Apr
When you stay at Hampton Inn Sikeston in Sikeston, you'll be near the airport, within a 5-minute drive of Central Park and Sikeston Depot Museum.
Hampton Inn Sikeston
Hospitality House Union City US 51

Hospitality House Union City US 51

2.5 out of 5
1221 W Reelfoot Ave, Union City, TN
Fully refundableReserve now, pay when you stay
The price is AU$105 per night from 3 May to 4 May
AU$105
includes taxes & fees
3 May - 4 May
With a stay at Hospitality House Union City US 51 in Union City, you'll be within a 5-minute drive of Reelfoot Shopping Center and County Market Place.
Hospitality House Union City US 51
For Larger Groups (Up To 24) Right on Reelfoot Lake--Private Dock And Pier

For Larger Groups (Up To 24) Right on Reelfoot Lake--Private Dock And Pier

Hornbeak
The price is AU$768 per night from 11 Apr to 12 Apr
AU$768
includes taxes & fees
11 Apr - 12 Apr
Located in Hornbeak, this vacation home is on the waterfront, within a 5-minute drive of Reelfoot Lake and Campbell's Point.
For Larger Groups (Up To 24) Right on Reelfoot Lake--Private Dock And Pier
Don't see what you're looking for?
See all available properties in East Prairie
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in East Prairie

Even though there aren't any hotels in East Prairie's centre, there are 13 options within 30 kilometres where you can hit the sack (and perhaps hit the mini bar).

Check in at Comfort Inn And Suites and Quality Inn and you'll be exploring your way through East Prairie in no time!

Still trying to book a place to crash? The Quality Inn Charleston and the Americas Best Value Inn & Suites Sikeston might just be what you're after. The first is 25 kilometres from downtown, while the latter is 30 kilometres away. Alternatively, you could travel 30 kilometres from central East Prairie to the Super 8 - Sikeston/Miner Area.

Attractions and Hotels Near East Prairie

Always on the hunt for your next great adventure? The wider Missouri region has some incredible things to throw yourself into as well. Nature lovers should plan an outing to East Prairie's stunning rolling hills and prairies. A few other gotta-see sights to stick on your hit list are history museums. Travellers with a serious appetite for adventure can also fill their days with a little rock climbing here.

Still haven't discovered your perfect room? You might just find a soft enough thread count in Dexter. You'll also be able to have some adventures at Stoddard County Civil War Memorial Cemetery and the Dexter Welcome Center Depot and Museum. Some of our recommended Dexter hotel options are the Oak Tree Inn Dexter and Hickory House Inn. Alternatively, you could stay in Dyersburg, 70 kilometres to the south of East Prairie, where you can choose from the Holiday Inn Express Hotel & Suites Dyersburg and Hampton Inn Dyersburg. While in Dyersburg, make sure you visit Shell City Park and Dyer County Courthouse.

Cape Girardeau features most of the retail and cultural highlights you'd expect from a place with about 38,000 residents. You'll find a good range of places to crash in Cape Girardeau, such as the Pear Tree Inn Cape Girardeau West and Holiday Inn Express Hotel & Suites Cape Girardeau I-55. Cape Girardeau can be found 75 kilometres to the north of East Prairie.

What are you waiting for? Book a hotel room, pack your case and you'll be in East Prairie before you can say lastminute.com.au!

East Prairie hotels essential information

Accommodation
80 hotels
Lowest Price
AU$96
Highest Price
AU$768
Popular hotels
Pear Tree Inn Sikeston, Best Western Plus Sikeston, Drury Inn & Suites Sikeston, MO, Holiday Inn Express & Suites Union City by IHG, New Orleans Inn Portageville , Days Inn and Suites by Wyndham Sikeston, Hampton Inn Sikeston, Hospitality House Union City US 51, For Larger Groups (Up To 24) Right on Reelfoot Lake--Private Dock And Pier

Most recent East Prairie hotel reviews

Holiday Inn Express & Suites Union City by IHG
Excellent
5 / 5
Very nice and clean. Keurig coffee makers and Dove shampoo and soap, in the rooms. Warm indoor swimming. Nice breakfast with bacon, sausage, and biscuits. It is right next to the Discovery Museum.
A verified traveller stayed at Holiday Inn Express & Suites Union City by IHG
Posted 1 day ago
Holiday Inn Express & Suites Union City by IHG

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.