Book Holiday Homes in Panama City

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Featured Holiday Homes in Panama City

Breathtaking Views Mansion w/King Beds

Breathtaking Views Mansion w/King Beds

Panamá
The price is AU$1,184 per night from 5 May to 6 May
AU$1,184
includes taxes & fees
5 May - 6 May
With a stay at this vacation home in Panama City (Bethania), you'll be within a 5-minute drive of Avenida Balboa and Via Espana.
Breathtaking Views Mansion w/King Beds
Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces

Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces

2 out of 5
Panamá
The price is AU$1,034 per night from 5 May to 6 May
AU$1,034
includes taxes & fees
5 May - 6 May
With a stay at this vacation home in Panama City, you'll be a 3-minute drive from Albrook Shopping Mall and 5 minutes from Avenida Balboa.
Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces
Charming Maison 4Bdr + 4Bth in Historic Center of Casco Viejo

Charming Maison 4Bdr + 4Bth in Historic Center of Casco Viejo

Casco Viejo
The price is AU$823 per night from 5 May to 6 May
AU$823
includes taxes & fees
5 May - 6 May
A stay at this vacation home places you in the heart of Panama City, within a 15-minute walk of Avenida Balboa and Cinta Costera.
Charming Maison 4Bdr + 4Bth in Historic Center of Casco Viejo
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Modern apartment in Casa Azul, Casco Viejo

Modern apartment in Casa Azul, Casco Viejo

Panamá
The price is AU$383 per night from 29 Apr to 30 Apr
AU$383
includes taxes & fees
29 Apr - 30 Apr
With a stay at this vacation home in Panama City (Casco Viejo), you'll be within a 5-minute drive of Avenida Balboa and Cinta Costera.
Modern apartment in Casa Azul, Casco Viejo
House in Punta Paitilla B19

House in Punta Paitilla B19

Panama
With a stay at this vacation home, you'll be centrally located in Panama City, just a 3-minute walk from Avenida Balboa and 9 minutes by foot from Cinta ...
House in Punta Paitilla B19
Oasis with pool near panama canal

Oasis with pool near panama canal

Panamá
The price is AU$426 per night from 6 Apr to 7 Apr
AU$426
includes taxes & fees
6 Apr - 7 Apr
Located in Panama City, this vacation home is within a 15-minute drive of Albrook Shopping Mall and Avenida Balboa.
Oasis with pool near panama canal
Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá

Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá

Panamá
With a stay at this vacation home in Panama City (Don Bosco), you'll be within a 15-minute drive of Multiplaza Pacific Mall and Avenida Balboa.
Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá
Two Floors Duplex in the middle of Panama City.

Two Floors Duplex in the middle of Panama City.

Panamá
With a stay at this vacation home in Panama City (Bethania), you'll be within a 5-minute drive of Via Espana and Multiplaza Pacific Mall.
Two Floors Duplex in the middle of Panama City.
Private Vacation Home: Pool, BBQ and more

Private Vacation Home: Pool, BBQ and more

Panamá
With a stay at this vacation home in Panama City, you'll be a 4-minute drive from Albrook Shopping Mall and 6 minutes from Cinta Costera.
Private Vacation Home: Pool, BBQ and more
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Panama City Holiday Houses

Do you love last minute road trips and late-night food runs and sunrises on the beach? Do words like “schedule” and “calendar” make you shout, “Don’t box me in!”? You might be a little bit of a rebel. But you’re a rebel with a cause: having a smashing holiday. Itinerary? What’s that? Our Panama City vacation homes are the perfect way for you to wing it.

Holiday houses in Panama City let you live life on your own terms. You’ll have so much space, you’ll wish you had more friends and family—but you can always invite over the neighbours. You can often have luxury amenities, but with all the attractions of Panama City in your backyard, budget holiday homes will do just fine, too. That will just leave you more dough to spend on the important things: cocktails, brunch, and local Panama City adventures, obvs.

If your adventure buddy happens to have fur and four legs, you just might find a pet-friendly holiday house in Panama City with your name on it.

No need to spend big bickies for a holiday beach house the size of Buckingham Palace—unless you’re really in trouble with bae. We’ve got a great selection of Panama City vacation homes with everything you need for a seriously amazing getaway. Throw out that daily planner and hit “reject” on all those meeting invites. You’re off to a place where there are no rules.

Panama City Holiday Homes essential information

Accommodation
65 Holiday Homes
Lowest Price
AU$102
Highest Price
AU$1,184
Popular accommodation
Breathtaking Views Mansion w/King Beds, Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces, Charming Maison 4Bdr + 4Bth in Historic Center of Casco Viejo, Modern apartment in Casa Azul, Casco Viejo, House in Punta Paitilla B19, Oasis with pool near panama canal, Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá, Two Floors Duplex in the middle of Panama City., Private Vacation Home: Pool, BBQ and more

Top trending hotels in Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AU$207 per night from 21 Apr to 22 Apr
AU$207
includes taxes & fees
21 Apr - 22 Apr
Centrally located in Panama City, Hotel Riu Plaza Panama is within a 15-minute walk of Crown Casino and Fiesta Casino.
Hotel Riu Plaza Panama
Riande Urban Hotel

Riande Urban Hotel

3.5 out of 5
El Cangrejo; Calle Eusebio A, Morales, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AU$115 per night from 5 Apr to 6 Apr
AU$115
includes taxes & fees
5 Apr - 6 Apr
With a stay at Riande Urban Hotel in Panama City (Bella Vista), you'll be within a 5-minute drive of Via Espana and Avenida Balboa.
Riande Urban Hotel
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AU$102 per night from 5 Apr to 6 Apr
AU$102
includes taxes & fees
5 Apr - 6 Apr
With a stay at Principe Hotel and Suites, you'll be centrally located in Panama City, within a 5-minute drive of Via Espana and Multiplaza Pacific Mall.
Principe Hotel and Suites
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JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AU$319 per night from 2 May to 3 May
AU$319
includes taxes & fees
2 May - 3 May
Centrally located in Panama City, JW Marriott Panama is within a 15-minute walk of Multiplaza Pacific Mall and Avenida Balboa.
JW Marriott Panama
Don't see what you're looking for?
See all available properties in Panama City
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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^Subject to availability and chosen travel dates.