Book Upstate South Carolina hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Upstate South Carolina

Cheap Upstate South Carolina hotels

Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is AU$245 per night from 20 Apr to 21 Apr
AU$245
includes taxes & fees
20 Apr - 21 Apr
With a stay at Hyatt Regency Greenville, you'll be centrally located in Greenville, within a 10-minute walk of The Peace Center and Falls Park on the Reedy.
Hyatt Regency Greenville
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Fully refundable
The price is AU$172 per night from 6 Apr to 7 Apr
AU$172
includes taxes & fees
6 Apr - 7 Apr
When you stay at Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG in Greenville, you'll be in a shopping district, a 3-minute drive from Haywood Mall ...
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is AU$468 per night from 6 Apr to 7 Apr
AU$468
includes taxes & fees
6 Apr - 7 Apr
Located in Greenville (Greenville Downtown), Grand Bohemian Lodge Greenville, Autograph Collection is steps from Falls Park on the Reedy and a 3-minute drive ...
Grand Bohemian Lodge Greenville, Autograph Collection
Save an average of 15% on thousands of hotels when you're signed in
Hyatt Place Greenville/Downtown

Hyatt Place Greenville/Downtown

3 out of 5
128 East Broad Street, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is AU$248 per night from 20 Apr to 21 Apr
AU$248
includes taxes & fees
20 Apr - 21 Apr
Hyatt Place Greenville/Downtown is in the heart of Greenville, within a 5-minute walk of The Peace Center and Falls Park on the Reedy.
Hyatt Place Greenville/Downtown
Cambria Hotel Greenville

Cambria Hotel Greenville

3 out of 5
135 Carolina Point Parkway, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is AU$198 per night from 13 Apr to 14 Apr
AU$198
includes taxes & fees
13 Apr - 14 Apr
With a stay at Cambria Hotel Greenville in Greenville, you'll be within a 15-minute drive of Haywood Mall and Bon Secours Wellness Arena.
Cambria Hotel Greenville
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is AU$146 per night from 13 Apr to 14 Apr
AU$146
includes taxes & fees
13 Apr - 14 Apr
With a stay at Best Western Plus Greenville I-385 Inn & Suites, you'll be centrally located in Greenville, a 4-minute drive from Haywood Mall and 8 minutes from ...
Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
The price is AU$163 per night from 8 Apr to 9 Apr
AU$163
includes taxes & fees
8 Apr - 9 Apr
With a stay at Best Western Plus Clemson Hotel & Conference Center in Clemson, you'll be within a 5-minute drive of Lake Hartwell and Clemson University.
Best Western Plus Clemson Hotel & Conference Center
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St, Clemson, SC
Fully refundableReserve now, pay when you stay
The price is AU$314 per night from 4 May to 5 May
AU$314
includes taxes & fees
4 May - 5 May
With a stay at The Shepherd Hotel Downtown Clemson in Clemson, you'll be a 4-minute walk from Clemson University and 10 minutes by foot from Lake Hartwell.
The Shepherd Hotel Downtown Clemson
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd, Greenville, SC
The price is AU$225 per night from 18 Apr to 19 Apr
AU$225
includes taxes & fees
18 Apr - 19 Apr
With a stay at Embassy Suites Greenville Golf Resort & Conference Center in Greenville, you'll be within a 10-minute drive of Haywood Mall and Bon Secours Wellness ...
Embassy Suites Greenville Golf Resort & Conference Center
Don't see what you're looking for?
See all available properties in Upstate South Carolina
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.

Upstate South Carolina hotels essential information

Accommodation
2,597 hotels
Lowest Price
AU$146
Highest Price
AU$468
Popular hotels
Hyatt Regency Greenville, Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG, Grand Bohemian Lodge Greenville, Autograph Collection, Hyatt Place Greenville/Downtown, Cambria Hotel Greenville, Best Western Plus Greenville I-385 Inn & Suites, Best Western Plus Clemson Hotel & Conference Center, The Shepherd Hotel Downtown Clemson, Embassy Suites Greenville Golf Resort & Conference Center

Most recent Upstate South Carolina hotel reviews

**Terms and Conditions apply.
^Subject to availability and chosen travel dates.