Find Midtown hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Midtown

Top trending hotels in Midtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$228 per night from 6 May to 7 May
AU$228
includes taxes & fees
6 May - 7 May
With a stay at Residence Inn by Marriott St Louis Downtown, you'll be centrally located in St. Louis, within a 5-minute drive of St. Louis Union Station and ...
Residence Inn by Marriott St Louis Downtown
Element St. Louis Midtown

Element St. Louis Midtown

3 out of 5
3763 Forest Park Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$257 per night from 4 May to 5 May
AU$257
includes taxes & fees
4 May - 5 May
Located in St. Louis (Midtown), Element St. Louis Midtown is within a 5-minute drive of St. Louis University and St. Louis Union Station.
Element St. Louis Midtown
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$233 per night from 1 May to 2 May
AU$233
includes taxes & fees
1 May - 2 May
With a stay at Hampton Inn St. Louis-Downtown (At the Gateway Arch), you'll be centrally located in St. Louis, a 8-minute walk from Gateway Arch and 14 minutes ...
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Save an average of 15% on thousands of hotels when you're signed in
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$220 per night from 14 May to 15 May
AU$220
includes taxes & fees
14 May - 15 May
With a stay at Drury Plaza Hotel St. Louis at the Arch, you'll be centrally located in St. Louis, just a 5-minute walk from Gateway Arch and 6 minutes by foot ...
Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$211 per night from 22 May to 23 May
AU$211
includes taxes & fees
22 May - 23 May
A stay at Hyatt Regency St. Louis at The Arch places you in the heart of St. Louis, within a 10-minute walk of Gateway Arch and Busch Stadium.
Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$183 per night from 25 May to 26 May
AU$183
includes taxes & fees
25 May - 26 May
With a stay at Clayton Plaza Hotel & Extended Stay in St. Louis (Clayton), you'll be within a 5-minute drive of Washington University in St. Louis and Forest ...
Clayton Plaza Hotel & Extended Stay
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is AU$217 per night from 23 May to 24 May
AU$217
includes taxes & fees
23 May - 24 May
With a stay at Renaissance St. Louis Airport Hotel in St. Louis (Berkeley), you'll be within a 15-minute drive of St. Louis Zoo and Hollywood Casino ...
Renaissance St. Louis Airport Hotel
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln, St. Ann, MO
Fully refundableReserve now, pay when you stay
The price is AU$166 per night from 28 Apr to 29 Apr
AU$166
includes taxes & fees
28 Apr - 29 Apr
With a stay at Pear Tree Inn St. Louis Airport, you'll be centrally located in St. Ann, within a 15-minute drive of Hollywood Casino Amphitheatre and Westport ...
Pear Tree Inn St. Louis Airport
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is AU$204 per night from 12 May to 13 May
AU$204
includes taxes & fees
12 May - 13 May
Located in Maryland Heights, Hollywood Casino & Hotel St. Louis is on a river, just a 3-minute walk from Hollywood Casino and a 4-minute drive from Hollywood ...
Hollywood Casino & Hotel St. Louis
Don't see what you're looking for?
See all available properties in Midtown
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Midtown Hotels

Haven’t you been dying to check out that swanky new coffee shop? What about the recently opened bar serving drinks in mason jars? And let’s not forget about the barber shops willing to give you a shaved-on-the-sides, long-on-top cut whenever you want. Don’t worry; we’ll help you find the best deals at hotels in Midtown.

This hip new ’hood will charm the-you-know-what off you. Midtown hotels are comfortable and affordable, and many offer amenities like room service for those late-night meals, as well as a pool to swim in. Some of these hotels will also have you near great shopping such as souvenir shops, clothing boutiques and everything in between. Don’t feel like leaving the hotel for dinner and drinks? Hang out in the lobby bar and meet some of your fellow travellers—you never what kinds of stories they have in their memory log.

There’s no point in going somewhere if you’re not going to stay where all the action is. lastminute.com.au gets you the best offers on where to stay in Midtown so you don’t have to waste endless hours searching online. The trip of a lifetime is at your fingertips. Click and go!

Midtown hotels essential information

Accommodation
1,785 hotels
Lowest Price
AU$166
Highest Price
AU$257
Popular hotels
Residence Inn by Marriott St Louis Downtown, Element St. Louis Midtown, Drury Plaza Hotel St. Louis at the Arch, Hyatt Regency St. Louis at The Arch, Renaissance St. Louis Airport Hotel, Pear Tree Inn St. Louis Airport, Clayton Plaza Hotel & Extended Stay, Hampton Inn St. Louis-Downtown (At the Gateway Arch), Hollywood Casino & Hotel St. Louis

Most recent Midtown hotel reviews