Find Isle of Palms hotels

More Flash, Less Cash - Take advantage of our Price Pledge** (even on luxey stays)

We keep it easy with the option to pay now or later on select accommodation

Book up 'til the last second - millions of rooms to crash tonight^

Check hotel availability in Isle of Palms

Top trending hotels in Isle of Palms

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL
Fully refundableReserve now, pay when you stay
The price is AU$431 per night from 2 Mar to 3 Mar
AU$431
includes taxes & fees
2 Mar - 3 Mar
With a stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area in Jacksonville (Southside), you'll be a 3-minute drive from Mayo Clinic Florida and ...
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N, Jacksonville Beach, FL
Fully refundableReserve now, pay when you stay
The price is AU$275 per night from 17 Feb to 18 Feb
AU$275
includes taxes & fees
17 Feb - 18 Feb
When you stay at Margaritaville Jacksonville Beach in Jacksonville Beach, you'll be on the beach, a 1-minute drive from Jacksonville Beach Pier and 10 minutes ...
Margaritaville Jacksonville Beach
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3 out of 5
1515 1st St N, Jacksonville Beach, FL
Fully refundableReserve now, pay when you stay
The price is AU$306 per night from 23 Feb to 24 Feb
AU$306
includes taxes & fees
23 Feb - 24 Feb
When you stay at Hampton Inn Jacksonville Beach/Oceanfront in Jacksonville Beach, you'll be on the beach, within a 15-minute drive of Mayo Clinic Florida and ...
Hampton Inn Jacksonville Beach/Oceanfront
Save an average of 15% on thousands of hotels when you're signed in
Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

3.5 out of 5
9300 Baymeadows Road, Jacksonville, FL
Fully refundableReserve now, pay when you stay
The price is AU$226 per night from 23 Feb to 24 Feb
AU$226
includes taxes & fees
23 Feb - 24 Feb
Located in Jacksonville (Southside), Embassy Suites by Hilton Jacksonville Baymeadows is within a 10-minute drive of St. Johns Town Center and University of ...
Embassy Suites by Hilton Jacksonville Baymeadows
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road, I-95 Exit 344 (Butler Boulevard), Jacksonville, FL
Fully refundableReserve now, pay when you stay
The price is AU$134 per night from 23 Feb to 24 Feb
AU$134
includes taxes & fees
23 Feb - 24 Feb
Located in Jacksonville (Southside), Wyndham Garden Jacksonville is within a 10-minute drive of St. Johns Town Center and University of North Florida.
Wyndham Garden Jacksonville
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr, Jacksonville, FL
Fully refundableReserve now, pay when you stay
The price is AU$357 per night from 27 Feb to 28 Feb
AU$357
includes taxes & fees
27 Feb - 28 Feb
Hyatt Regency Jacksonville is centrally located in Jacksonville, a 4-minute walk from Florida Theatre and 8 minutes by foot from Times-Union Center for the Performing ...
Hyatt Regency Jacksonville
DoubleTree by Hilton Hotel Jacksonville Riverfront

DoubleTree by Hilton Hotel Jacksonville Riverfront

4 out of 5
1201 Riverplace Boulevard, Jacksonville, FL
Fully refundableReserve now, pay when you stay
The price is AU$247 per night from 16 Mar to 17 Mar
AU$247
includes taxes & fees
16 Mar - 17 Mar
DoubleTree by Hilton Hotel Jacksonville Riverfront is centrally located in Jacksonville, a 5-minute walk from Museum of Science and History and a 3-minute drive ...
DoubleTree by Hilton Hotel Jacksonville Riverfront
Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

3 out of 5
14565 Duval Rd, Jacksonville, FL
Fully refundableReserve now, pay when you stay
The price is AU$177 per night from 23 Feb to 24 Feb
AU$177
includes taxes & fees
23 Feb - 24 Feb
With a stay at Hyatt Place Jacksonville Airport in Jacksonville (Northside), you'll be within a 15-minute drive of Jacksonville Cruise Terminal and Jacksonville ...
Hyatt Place Jacksonville Airport
Omni Amelia Island Resort & Spa

Omni Amelia Island Resort & Spa

4 out of 5
39 Beach Lagoon Road, Fernandina Beach, FL
The price is AU$575 per night from 5 Mar to 6 Mar
AU$575
includes taxes & fees
5 Mar - 6 Mar
With a stay at Omni Amelia Island Resort & Spa in Fernandina Beach, you'll be 3.3 mi (5.3 km) from Fort George Island Cultural State Park and 11.4 mi (18.3 km) ...
Omni Amelia Island Resort & Spa
Don't see what you're looking for?
See all available properties in Isle of Palms
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Isle of Palms Hotels

Haven’t you been dying to check out that swanky new coffee shop? What about the recently opened bar serving drinks in mason jars? And let’s not forget about the barber shops willing to give you a shaved-on-the-sides, long-on-top cut whenever you want. Don’t worry; we’ll help you find the best deals at hotels in Isle of Palms.

This hip new ’hood will charm the-you-know-what off you. Isle of Palms hotels are comfortable and affordable, and many offer amenities like room service for those late-night meals, as well as a pool to swim in. Some of these hotels will also have you near great shopping such as souvenir shops, clothing boutiques and everything in between. Don’t feel like leaving the hotel for dinner and drinks? Hang out in the lobby bar and meet some of your fellow travellers—you never what kinds of stories they have in their memory log.

There’s no point in going somewhere if you’re not going to stay where all the action is. lastminute.com.au gets you the best offers on where to stay in Isle of Palms so you don’t have to waste endless hours searching online. The trip of a lifetime is at your fingertips. Click and go!

Isle of Palms hotels essential information

Accommodation
3,070 hotels
Lowest Price
AU$134
Highest Price
AU$575
Popular hotels
Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Margaritaville Jacksonville Beach, Embassy Suites by Hilton Jacksonville Baymeadows, Wyndham Garden Jacksonville, Omni Amelia Island Resort & Spa, DoubleTree by Hilton Hotel Jacksonville Riverfront, Hyatt Regency Jacksonville, Hampton Inn Jacksonville Beach/Oceanfront, Hyatt Place Jacksonville Airport

Most recent Isle of Palms hotel reviews